Results 181 to 190 of about 501,011 (326)

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

EXPLORING THE REGENERATIVE CAPACITY OF ARCHITECTURE IN THE ANTHROPOCENE ERA THROUGH ANNA HERINGER'S ARCHITECTURE

open access: yesLivenarch+ Journal
In the Anthropocene era, human-driven destruction of nature, primarily caused by diverse industries worldwide, is significantly worsening the degenerative impacts on nature at varying scales globally.
Kübra Sağlam, Kübra Bıyuk Öksüz
doaj  

A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response

open access: yesAdvanced Science, EarlyView.
Although Zinc(II) complexes are effective in photodynamic therapy, their efficacy is limited by the poor tissue penetration of light. This work introduces a novel zinc(II) complex for sonodynamic therapy. Under ultrasound activation, it generates substantial singlet oxygen, induces pyroptosis in breast cancer cells, and promotes anti‐tumor immune ...
Sijie Wen   +8 more
wiley   +1 more source

Hyaluronic Acid Hydrogel Implants for Sustained Release of Oxaliplatin and Resiquimod to Prevent Hepatocellular Carcinoma Recurrence Post‐Radiofrequency Ablation

open access: yesAdvanced Science, EarlyView.
Preparation of a biopolymer‐based immune implant (BI) for the sustained release of R848 and oxaliplatin (OXA), enabling immune activation and preventing recurrence after radiofrequency ablation (RFA) treatment in hepatocellular carcinoma (HCC). Abstract Hepatocellular carcinoma (HCC) remains a global challenge due to limited therapies and high ...
Yuezhan Shan   +9 more
wiley   +1 more source

Retinal pigment epithelium stress following intravitreal ganciclovir: a novel insight from clinical spectrum. [PDF]

open access: yesJ Ophthalmic Inflamm Infect
Du KF   +7 more
europepmc   +1 more source

Automated Benchmarking of Variable‐Property Soft Robotic Fingertips to Enable Task‐Optimized Sensor Selection

open access: yesAdvanced Science, EarlyView.
Sensorized fingertips are needed to unlock robotic dexterity, versatility, and diverse interactions. Here, 15 identically‐shaped robotic fingertips are benchmarked by a fully automated toolchange system, covering eight different materials and six broadly‐ranging sensing mechanisms.
David Hardman   +5 more
wiley   +1 more source

Accelerated brain age in Moyamoya disease patients: a deep learning approach and correlation with disease severity. [PDF]

open access: yesFront Neurosci
Li W   +9 more
europepmc   +1 more source

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