Results 41 to 50 of about 327,239 (305)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

An outbreak of Coxsackievirus A6–associated hand, foot, and mouth disease in a kindergarten in Beijing in 2015

BMC Pediatrics, 2018
Background Coxsackievirus A6 (CVA6) is one of the major agents to cause hand, foot and mouth disease (HFMD) outbreaks globally. The objective of this study is to investigate the epidemiologic and clinical manifestations of CVA6 outbreak, and thus guide ...
Jie Li, Rong Zhu, Da Huo, Yiwei Du, Yuxiang Yan, Zhichao Liang, Yanxia Luo, Yang Yang, Lei Jia, Lijuan Chen, Quanyi Wang, Yan He   +11 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

COVID-19 prevention measures reduce dengue spread in Yunnan Province, China, but do not reduce established outbreak

Emerging Microbes and Infections, 2022
The COVID-19 pandemic and measures against it provided a unique opportunity to understand the transmission of other infectious diseases and to evaluate the efficacy of COVID-19 prevention measures on them. Here we show a dengue epidemic in Yunnan, China,
Z.Y. Sheng, M. Li, R. Yang, Y.H. Liu, X.X. Yin, J. R. Mao, Heidi E. Brown, J. An, H.N. Zhou, P.G. Wang   +9 more
doaj   +1 more source

The information content of capital controls [PDF]

Journal of International Money and Finance, 2020
Capital controls, policy measures used by governments to regulate cross-country financial flows, have become standard policy options in many emerging market economies. This paper will focus on what capital controls reveal about the state of the economy and the implications of such revelation for policy efficacy.
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Development of a predictive model for risk factors of multidrug-resistant bacterial pneumonia in critically ill post-neurosurgical patients

Frontiers in Public Health
BackgroundMachine learning models have emerged as pivotal tools for enhancing the predictive accuracy of multidrug-resistant bacterial pneumonia (MDR-BP) risk in critically ill patients following neurosurgery procedures.
Aixiang Hu, Dayan Ma, Yanni Lei, Fangqiang Li, Xi Wang, Yuewei Zhang   +5 more
doaj   +1 more source

Clinical characteristics of abruptly increased paediatric patients with Omicron BF.7 or BA.5.2 in Beijing

Virology Journal, 2023
Background The coronavirus disease 2019 outbreak has hit Beijing since mid-Nov, 2022, with soaring growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children.
Lei Yu, Congying Wang, Xiaoyun Li, Xinning Wang, Yingying Kang, Xiaomei Ma, Rui Sun, Yu Sun, Runan Zhu, Liping Jia, Yao Yao, Xiaohui Li, Daitao Zhang, Yang Pan, Bing Lv, Jing Yuan, Linqing Zhao, Qinglong Gu, Jian Zhang   +18 more
doaj   +1 more source

Temporary controls on capital inflows [PDF]

Journal of International Economics, 2002
Abstract During the past decade a number of countries imposed capital controls that had two distinguishing features: they were asymmetric, in that they were designed principally to discourage capital inflows, and they were temporary. This paper studies formally the consequences of these policies, calibrates their potential effectiveness, and assesses
Reinhart, Carmen, Smith, R Todd
openaire   +2 more sources