Results 161 to 170 of about 754,643 (296)

Bridging the digital health divide: digital endowment, informal social participation, and health inequality among older adults. [PDF]

BMC Health Serv Res
Cui Y, Bao H, Wen K, Wen H.
europepmc   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

Advanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo, Xiaoyan Guo, Jian Wei, Miaowen Jiang, Qifa Su, Xian Xia, Zhuozhou Li, Rong Cai, Jianguo Ma, Bo Fu, Ming Li, Jing Zhong, Lijun Xu, Xunming Ji   +13 more
wiley   +1 more source

Self-fulfillment Expectations, Speculation Attacks, and Capitol Controls [PDF]

This paper examines the endogenous implementation of capital controls in the context of a fixed exchange rate regime. It is shown that if there exists a non-zero probability that the policymaker's response to a speculative attack on official foreign ...
Alan C. Stockman, Harris Dellas
core  

Pathways to self-reliance: a pilot trial of an integrated livelihoods and psychosocial program for displaced women in Colombia. [PDF]

Confl Health
Stark L, Roa AH, Castellar D, Monar A, Venegas M, Leeson K, Gebrekidan F, Meerdink N, Seff I.   +8 more
europepmc   +1 more source

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

Advanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu, Xiaoyue Xu, Dan Xu, Hui Zhang, Nan Wang, Yang Yang, Qian Chen, Shunjie Chen, Cheng Li   +8 more
wiley   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Multi-Omics Reveal the Potential Associations of <i>Streptococcus</i>, 13'-Hydroxy-Alpha-Tocopherol and Glutathione Metabolism in Children with Chronic Rhinosinusitis with Nasal Polyps. [PDF]

J Inflamm Res
Jia C, Liu X, Liu W, Yao X, Chen X, Zhao J, Wang P, Ge W, Han Y.   +8 more
europepmc   +1 more source

Modulating Local Electronic Structure via Cluster Engineering on Cobalt Phosphide for Efficient Water/Seawater Splitting

Advanced Science, EarlyView.
The heterostructure benefits from the high dispersion of FeOx nanoclusters on the porous CoxP substrate, while the interfacial bonds Fe‐O‐Co enhance charge transport and redistribution, resulting in excellent oxygen evolution reaction performance and strong potential for practical applications.
Cheng Gong, Fengying Pan, Pengpeng Zhang, Yuhan Xie, Yaojie Lei, Xiaobo Zheng, Dinushi Munasinghe Mudiyanselage, Hong Gao, Jinqiang Zhang, Yufei Zhao, Guoxiu Wang, Hao Liu   +11 more
wiley   +1 more source

Effects of T2-high asthma heterogeneity and inhaled corticosteroid on airway and metabolic profiles: A multi-omic approach. [PDF]

J Transl Int Med
Duan Y, Gu Z, Liu T, Song C, Wang Y, Wang W, Jin R, Wang X, Zhang Y, Huang K.   +9 more
europepmc   +1 more source

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source