Results 21 to 30 of about 2,217,595 (292)

Towards reviving post-Olympic Athens as a cultural destination [PDF]

open access: yes, 2012
This paper examines the effects of global change on the status and qualities of the Greek national capital, Athens, focusing on how they affect the development of cultural tourism in the city.
Alevizopoulou M.   +26 more
core   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Data augmentation alters feature importance in XGBoost for CVD prediction

open access: yesScientific Reports
Machine learning models are powerful tools for cardiovascular disease (CVD) prediction, but their performance is often limited by dataset size and class imbalance.
Shuai Chang   +3 more
doaj   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Paint Loss Detection and Segmentation Based on YOLO: An Improved Model for Ancient Murals and Color Paintings

open access: yesHeritage
Paint loss is one of the major forms of deterioration in ancient murals and color paintings, and its detection and segmentation are critical for subsequent restoration efforts.
Yunsheng Chen   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cultural Capital as the Basis for Developing Tourism at Kuta Traditional Village [PDF]

open access: yes, 2012
This study was conducted at Kuta Traditional Village, the first traditional village which has been growing fast as a tourist destination. Its tourist facilities are integrated with the facilities needed by the villagers.
KETUT, SUMADI
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Habitus and cultural capital

open access: yesFields, 2021
The aim of this research was, ‘To explore if Pierre Bourdieu’s concepts of ‘Habitus’ and ‘Cultural Capital’ differently impact Huddersfield University students participating in the ‘Final Year Project Module for the Social Sciences (FYP)’. The rationale
Jay Schofield
doaj   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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