Results 61 to 70 of about 21,521 (265)

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

ANALISIS BELANJA MODAL DAN FAKTOR-FAKTOR YANG MEMPENGARUHINYA PADA PEMERINTAH KABUPATEN/KOTA DI INDONESIA

open access: yesJurnal Akuntansi Universitas Jember, 2016
Infrastructure development is one of important aspects in achieving high economic growth of all regions in Indonesia. On the other hand, portion of capital expenditure in the budget of Local Government spending a very important component for the ...
sugiyanta sugiyanta
doaj   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

open access: yesAdvanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

open access: yesAdvanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia   +13 more
wiley   +1 more source

The Incremental Information Content of Capital Expenditures [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2006
This study examines whether capital expenditures provide value relevant information which is incremental to that of current earnings. Models in accounting or capital expenditures yield information about a firm's future earnings that is not captured by ...
Mohammad Esmaeel Fadaie Nejad   +1 more
doaj  

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

open access: yesAdvanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu   +7 more
wiley   +1 more source

ANALISIS PENGARUH PAD, DAU DAN DAK TERHADAP BELANJA MODAL DAN BELANJA BARANG DAN JASA KOTA DAN KABUPATEN DI PROVINSI JAWA TIMUR TAHUN 2006-2012

open access: yesJurnal Ekonomi Modernisasi, 2013
Decentralized system of local government put as executor and promoter of development in the area to organize and define their own regional development activities in accordance with the priority needs of the local community.
Sugeng Haryanto
doaj   +1 more source

FREE MARKET ECONOMY AND THE EFFECT OF MACROECONOMIC FACTORS ON GROWTH: THE CASE OF SOUTH KOREA

open access: yesEkonomi Maliye İşletme Dergisi, 2020
The aim of this study is to empirically analyze the impact of capital stock, employment level, human capital, total factor productivity, openness policy, government spending and household consumption on growth in South Korea between 1965 and 2017 ...
Gözde ARSLAN, Hicran KASA
doaj   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

open access: yesAdvanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu   +18 more
wiley   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

open access: yesAdvanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas   +12 more
wiley   +1 more source

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