Results 141 to 150 of about 700,751 (306)

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

open access: yesAdvanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen   +12 more
wiley   +1 more source

Modulating Local Electronic Structure via Cluster Engineering on Cobalt Phosphide for Efficient Water/Seawater Splitting

open access: yesAdvanced Science, EarlyView.
The heterostructure benefits from the high dispersion of FeOx nanoclusters on the porous CoxP substrate, while the interfacial bonds Fe‐O‐Co enhance charge transport and redistribution, resulting in excellent oxygen evolution reaction performance and strong potential for practical applications.
Cheng Gong   +11 more
wiley   +1 more source

CAPITAL MARKETS AND THE COST OF CAPITAL [PDF]

open access: yes
The paper introduces the engrossing subject of the cost of capital obtained through the capital funds markets and helps to set off in bold relief the conditioning relationship of long-run operating decisions to short-run internal and external decision ...
Lect. Dana Adriana Lupşa-Tătaru Ph. D   +1 more
core  

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

open access: yesAdvanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng   +6 more
wiley   +1 more source

Do Debt Flows Crowd Out Equity Flows Or the Other Way Round? [PDF]

open access: yes
In the presence of asymmetric information, the stage at which financing decisions are made about investment projects in a small open economy is crucial for the composition of international capital inflows as well as for the efficiency of channeling ...
Assaf Razin, Chi-Wa Yuen, Efraim Sadka
core  

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang   +9 more
wiley   +1 more source

Financing Development in the UNECE Emerging Markets [PDF]

open access: yes
This essay discusses the challenges in financing economic development in the eastern European and CIS economies. The advantages and pitfalls of extensively relying external capital are explored.Financing for development, external finance, capital flows ...
Robert Shelburne
core  

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