Results 171 to 180 of about 2,618,344 (297)

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

The impact of the 2019 revision of China's drug administration law on the innovative output of pharmaceutical and biotechnology enterprises-a quasi-natural experimental study using sharp regression discontinuity design. [PDF]

Front Med (Lausanne)
Zhu Y, Liu Y, Chen Y, Meng L.
europepmc   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

The past, present, and future of peaking thermal power plants in the United States. [PDF]

iScience
Vanatta M, Sergi B, Cole W, Denholm P, Mai T.   +4 more
europepmc   +1 more source

Roadmap for High‐Throughput Ceramic Materials Synthesis and Discovery for Batteries

Advanced Energy Materials, EarlyView.
This work examines ceramic synthesis through the lens of high‐throughput synthesis and optimization, identifying opportunities for faster, adaptable routes. It emphasizes flexible liquid precursor–to–solid film methods over slower solid‐state approaches and highlights computer‐aided decision making to optimize both material properties and device ...
Jesse J. Hinricher, Katarzyna P. Sokol, Philipp Simons, Kun Joong Kim, Michael Foshey, Yunsheng Tian, Thorben Prein, Lincoln J. Miara, Elsa Olivetti, Wojciech Matusik, Jennifer L. M. Rupp   +10 more
wiley   +1 more source

Correction: New insights into the treatment of nasopharyngeal carcinoma in children, adolescents, and young adults: a retrospective study. [PDF]

Front Immunol
Ren M, Tian J, Han M, Sun S, Wang K, Wu R, Yuan M, Yi J, Ma F, Li S.   +9 more
europepmc   +1 more source

Selective Electrolysis of Water Under Artificial Seawater Conditions Using Transition Metal Borate Anodes

Advanced Energy Materials, EarlyView.
The borate‐based cobalt‐iron catalyst promotes selective oxidation of water rather than chlorine evolution reaction during electrolysis of seawater. When integrated into a zero‐gap electrolyzer prototype, this catalyst supports robust splitting of artificial seawater into oxygen and hydrogen on an extended timescale.
Ananta R. Fareza, Hank Garg, Luis Miguel Azofra, Darcy Simondson, Tam D. Nguyen, Mohamed R. Rizk, Khang N. Dinh, Rosalie K. Hocking, Douglas R. MacFarlane, Hoang‐Long Du, Alexandr N. Simonov   +10 more
wiley   +1 more source

Correction: Preclinical evaluation of 6-Gingerol in modulating gut microbiota and SCFAs to mitigate <i>Clostridium difficile</i>-associated diarrhea in mice. [PDF]

Front Chem
Ma FZ, Zhu L, Li M, Tang ZW, Yu XH, Zhang CE, Ma ZJ.   +6 more
europepmc   +1 more source

Protecting natural capital for human wellbeing and sustainable development [PDF]

, 2010
Groot, R.S., de
core   +1 more source