Results 1 to 10 of about 75,405 (147)

Robust Capital Regulation [PDF]

SSRN Electronic Journal, 2011
Banks’ leverage choices represent a delicate balancing act. Credit discipline argues for more leverage, while balance-sheet opacity and ease of asset substitution argue for less. Meanwhile, regulatory safety nets promote ex post financial stability, but also create perverse incentives for banks to engage in correlated asset choices and to hold little ...
Acharya, Viral V, Mehran, Hamid, Schuermann, Til, Thakor, Anjan   +3 more
openaire   +6 more sources

The role of roof plate-specific spondins in liver homeostasis and disease

Liver Research, 2022
As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang, Wenhui Yue, Hang Zhang, Yue Gao, Lin Yang, Liying Li   +5 more
doaj   +1 more source

Clinical analysis of second-trimester pregnancy termination after previous caesarean delivery in 51 patients with placenta previa and placenta accreta spectrum: a retrospective study

BMC Pregnancy and Childbirth, 2021
Backgrounds Pregnancy termination during the second trimester in patients with placenta previa and placenta accreta spectrum (PAS) is a complex and challenging clinical problem.
Qiaofei Hu, Changdong Li, Lanrong Luo, Jian Li, Xiaofeng Zhang, Suwen Chen, Xiaokui Yang   +6 more
doaj   +1 more source

Optimal Capital Regulation [PDF]

SSRN Electronic Journal, 2017
Nous étudions la réglementation sur les fonds propres des banques assortie d’une contrainte d’efficience dans un modèle intégrant des exigences de fonds propres imposées par le marché. Les banques détiennent des volants de fonds propres pour se protéger contre une perte soudaine d’accès au financement. Toutefois, dans le modèle, les banques décident de
Moyen, Stéphane, Schroth, Josef
openaire   +2 more sources

Exploring Higher Capital Requirements in Nepal Under Basel III: A Qualitative Approach

International Journal of Qualitative Research, 2023
This paper explored the impact of capital regulation on the banking industry in Nepal and sought to understand the reasons behind the requirements for higher capital in the country compared to global standards set by the Basel Committee on Banking ...
Anuj Acharya, Bidush Nepal, Ananta Raj Kafle   +2 more
doaj   +1 more source

Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury

Cell Reports, 2023
Summary: Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear.
Weiyang Li, Yuanru Yang, Lin Yang, Na Chang, Liying Li   +4 more
doaj   +1 more source

Dual Targeting of Angipoietin‐1 and von Willebrand Factor by microRNA‐671‐5p Attenuates Liver Angiogenesis and Fibrosis

Hepatology Communications, 2022
Angipoietin‐1 (Angpt1) and von Willebrand factor (VWF) are two important angiogenic molecules that can drive pathologic angiogenesis and progression of liver fibrosis in our previous study.
Le Yang, Wenhui Yue, Hang Zhang, Zhi Zhang, Renmin Xue, Chengbin Dong, Fuquan Liu, Na Chang, Lin Yang, Liying Li   +9 more
doaj   +1 more source

Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome

Frontiers in Immunology, 2020
NLR family pyrin domain containing 3 (NLRP3) inflammasome accompanies chronic liver injury and is a critical mediator of inflammation-driven liver fibrosis. Sphingosine 1-phosphate (S1P)/S1P Receptor (S1PR) signaling participates in liver fibrogenesis by
Lei Hou, Le Yang, Na Chang, Xinhao Zhao, Xuan Zhou, Chengbin Dong, Fuquan Liu, Lin Yang, Liying Li   +8 more
doaj   +1 more source

Silencing IQGAP1 alleviates hepatic fibrogenesis via blocking bone marrow mesenchymal stromal cell recruitment to fibrotic liver

Molecular Therapy: Nucleic Acids, 2022
IQ motif-containing guanosine triphosphatase (GTPase)-activating protein 1 (IQGAP1) is a cytosolic scaffolding protein involved in cell migration. Our previous studies suggest sphingosine 1-phosphate (S1P) triggers bone marrow (BM) mesenchymal stromal ...
Yuehan Ma, Na Chang, Yuran Liu, Fuquan Liu, Chengbin Dong, Lei Hou, Changbo Qi, Lin Yang, Liying Li   +8 more
doaj   +1 more source

Cannabinoid Receptor 1/miR-30b-5p Axis Governs Macrophage NLRP3 Expression and Inflammasome Activation in Liver Inflammatory Disease

Molecular Therapy: Nucleic Acids, 2020
Nod-like receptor (NLR) family pyrin domain containing 3 (NLRP3) has been regarded as an important initiator or promoter in multiple inflammatory diseases.
Le Yang, Lei Tian, Zhi Zhang, Xuan Zhou, Xiaofang Ji, Fuquan Liu, Chengbin Dong, Lei Hou, Xinhao Zhao, Na Chang, Lin Yang, Liying Li   +11 more
doaj   +1 more source