Results 11 to 20 of about 1,065,416 (313)

Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/Gαi/o/ROS/p38 MAPK Signaling Pathway

open access: yesCells, 2020
Neutrophils play an essential role in the control of inflammatory diseases. However, whether cannabinoid receptors (CBs) play a role in neutrophil chemotaxis and NETosis in sterile liver inflammation remains unknown.
Xuan Zhou   +6 more
doaj   +1 more source

Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

open access: yesFrontiers in Immunology, 2017
Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation.
Lei Tian   +8 more
doaj   +1 more source

Necroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis

open access: yesCell Death and Disease, 2023
Biliary atresia (BA) is a severe inflammatory and fibrosing neonatal cholangiopathy disease characterized by progressive obstruction of extrahepatic bile ducts, resulting in cholestasis and progressive hepatic failure.
Shen Yang   +12 more
doaj   +1 more source

Regulatory governance pathways to improve the efficacy of Australian food policies

open access: yesAustralian and New Zealand Journal of Public Health, 2022
Background: Effective regulatory governance, which entails the actors, processes and contexts within which policies are developed, designed and implemented, is crucial for food policies to improve food environments, consumer behaviour and diet‐related ...
Yandisa Ngqangashe, Sharon Friel
doaj   +1 more source

Single-Cell Transcriptomes Reveal Characteristic Features of Mouse Hepatocytes with Liver Cholestatic Injury

open access: yesCells, 2019
Hepatocytes are the main parenchymal cells of the liver and play important roles in liver homeostasis and disease process. The heterogeneity of normal hepatocytes has been reported, but there is little knowledge about hepatocyte subtype and distinctive ...
Na Chang   +8 more
doaj   +1 more source

Prognostic value of the ascites characteristics in pseudomyxoma peritonei originating from the appendix

open access: yesFrontiers in Surgery, 2023
BackgroundPseudomyxoma peritonei (PMP) is a rare disease, with the overall survival (OS) influenced by many factors. To date, no ascites characteristics have been reported to predict OS of patients with PMP.
Bing Wang   +16 more
doaj   +1 more source

The combination of hand grip strength and modified Glasgow prognostic score predicts clinical outcomes in patients with liver cancer

open access: yesFrontiers in Nutrition, 2023
PurposePrevious studies have shown that both hand grip strength (HGS) and the modified Glasgow Prognostic Score (mGPS) are associated with poor clinical outcomes in patients with liver cancer.
Yue Chen   +45 more
doaj   +1 more source

Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway

open access: yesHepatology Communications, 2020
It is well known that excessive cholesterol accumulation within hepatocytes deteriorates nonalcoholic fatty liver disease (NAFLD). Augmenter of liver regeneration (ALR) has been reported to alleviate NAFLD through anti‐apoptosis; however, whether ALR ...
Xin Wang   +7 more
doaj   +1 more source

Novel Diagnostic and Prognostic Tools for Lung Cancer Cachexia: Based on Nutritional and Inflammatory Status

open access: yesFrontiers in Oncology, 2022
BackgroundCachexia is one of the most common complications affecting lung cancer patients that seriously affects their quality-of-life and survival time. This study aimed to analyze the predictors and prognostic factors of lung cancer cachexia as well as
Chen-An Liu   +36 more
doaj   +1 more source

Capital Adequacy Regulation

open access: yes, 2020
This chapter aims to provide a concise overview of the capital adequacy regulation, importance of the regulation, and evolution of the capital adequacy regulation. Bank capital executes the significant role of preventing the bank from failure and acts as a buffer against possible losses.
Aysa Siddika, Razali Haron
openaire   +3 more sources

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