Results 31 to 40 of about 904,269 (335)

Copula-Based Risk Aggregation and the Significance of Reinsurance

open access: yesRisks
Insurance companies need to calculate solvency capital requirements in order to ensure that they can meet their future obligations to policyholders and beneficiaries.
Alexandra Dias   +2 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

A Linear Mathematical Formulation to Minimize Intermediate Fluid Flow in Batch Heat Exchanger Networks

open access: yesChemical Engineering Transactions, 2018
In heat integration of batch process, heat storage plays an important role. In batch processes heat can be transported from a prior time zone to later time zone via heat storage.
Nitin Dutt Chaturvedi
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Using risk simulation to reduce the capital cost requirement for a programme of capital projects

open access: yesBusiness, Management and Education, 2017
This paper combines various concepts related to (i) project risk management, (ii) Monte Carlo simulation, (iii) project contingency cost estimation, and (iv) the relationship between project and programme risks, to illustrate that the contingency ...
Francois Joubert, Leon Pretorius
doaj   +1 more source

On Risk Management of Mortality and Longevity Capital Requirement: A Predictive Simulation Approach

open access: yesRisks, 2023
In the insurance industry, life insurers are required by regulators to meet capital requirements to avoid insolvency caused by, for example, sudden mortality changes due to the COVID-19 pandemic.
Shuai Yang, Kenneth Q. Zhou
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Determinants of behaviour of working capital requirements of BSE listed companies: An empirical study using co-integration techniques and generalised method of moments

open access: yesCogent Economics & Finance, 2020
The paper investigates the determinants of working capital to forecast the future requirement of working capital of BSE-listed top 150 companies in India.
Rakesh Kumar Sharma   +2 more
doaj   +1 more source

Excellence scientifique transnationale et disqualification des sciences humaines et sociales nationales en Algérie

open access: yesRevue d’Histoire des Sciences Humaines, 2023
This article aims at showing how the linguistic and political opposition between Arabic speakers and French speakers that had dominated the Algerian academic field from the 1970s to the 1990s was transformed during the ‘black decade’ (1990-2000) into a ...
Kamel Chachoua
doaj   +1 more source

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