Results 141 to 150 of about 161,683 (291)

Techno‐Economic Analysis of Polylactic Acid from Corn Stover: Understanding Uncertainty and Variability via Artificial Intelligence Tools

open access: yesAdvanced Sustainable Systems, EarlyView.
This study analyses the uncertainty and variability existing in the economic performance of polylactic acid (PLA) production, via integrating techno‐economic analysis with process models and Monte Carlo simulation enabled by artificial intelligence. The results show that the minimum selling price varies from $2,107 to $3076/t PLA.
Yinqiao Wang   +5 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

open access: yesAdvanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang   +51 more
wiley   +1 more source

Effect of Market Timing in the Capital Structure of Latin America

open access: diamond, 2016
Andréia Carpes Dani   +3 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

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