Results 31 to 40 of about 218 (198)
Women Informal Business Tourists in Urban Southern Africa: Circuits, Drivers and Challenges [PDF]
Across sub-Saharan Africa, a substantial economy benefits from informal business tourism. In Southern Africa, the central element in informal business tourism is women's activities as informal cross-border shoppers and traders.
Rogerson, Christian M. +1 more
core +2 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
We highlight the salient characteristics and implications of the seminal contributions in the field of vintage capital growth theory (proposed entry for the new Palgrave dictionary of economics, 2nd edition).
Raouf, BOUCEKKINE +2 more
openaire +5 more sources
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Capitalness is contingent: tourism and national capitals in a globalised world [PDF]
National capitals play a central role in tourism in a globalised world, but their special qualities – their capitalness – can be elusive. This article argues that tourism representation is at the heart of capitalness and shapes the ways in which capitals
Maitland, R., Maitland, R.
core +2 more sources
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
The socioeconomic impacts of public and private investments in infrastructure development in Burkina Faso [PDF]
Thesis (PhD)--Stellenbosch University, 2023.ENGLISH SUMMARY: Under Burkina Faso’s National Plan for Economic and Social Development (PNDES), a first phase of an ambitious programme for infrastructure development was adopted for 2016-2020.
Ouedraogo, Yacouba
core +1 more source
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source

