Results 11 to 20 of about 16,152 (200)

Biomolecular Interaction Prediction in the Pre- and Post-AlphaFold Era: The 8th CAPRI Evaluation [PDF]

Proteins: Structure, Function and Bioinformatics
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Alexandre Bonvin, Shoshana Wodak, Guillaume Brysbaert   +2 more
exaly   +3 more sources

Integrating the MARTINI2 coarse-grained force field into HADDOCK3 for faster modeling of large biomolecular complexes. [PDF]

Protein Sci
Abstract The integration of coarse‐grained (CG) approaches into docking workflows offers a powerful strategy for modeling large biomolecular assemblies with reduced computational costs. We present here the implementation of the MARTINI2 CG force field into the HADDOCK3 integrative modeling platform.
Versini R, Reys V, Kravchenko A, Honorato RV, Bonvin AMJJ.   +4 more
europepmc   +2 more sources

Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis. [PDF]

Arthritis Care Res (Hoboken)
Objective We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Cunningham C, McPherson M, Lim L, Berard RA, Berkowitz M, Proulx-Gauthier JP, Feldman BM, Johnson N, Rumsey DG, Schmeling H, Tucker LB, Loughin T, Houghton KM, Guzman J, Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry Investigators.   +14 more
europepmc   +2 more sources

Experimental optimization of the CAPRI process [PDF]

, 2011
An experimental study was carried out concerning the optimization of catalyst type, operating conditions, addition of water and hydrogen for use in the THAI-CAPRI process and is reported.
Shah, Amjad
core   +7 more sources

Understanding personalized dynamics to inform precision medicine: a dynamic time warp analysis of 255 depressed inpatients

BMC Medicine, 2020
Background Major depressive disorder (MDD) shows large heterogeneity of symptoms between patients, but within patients, particular symptom clusters may show similar trajectories.
K. Hebbrecht, M. Stuivenga, T. Birkenhäger, M. Morrens, E. I. Fried, B. Sabbe, E. J. Giltay   +6 more
doaj   +1 more source

Clinically assessed and perceived unmet mental health needs, health care use and barriers to care for mental health problems in a Belgian general population sample

BMC Psychiatry, 2022
Background Mental health problems often remain undetected and untreated. Prior research suggests that this is mainly due to a lack of need-perception and attitudinal barriers.
Eva Rens, Joris Michielsen, Geert Dom, Roy Remmen, Kris Van den Broeck   +4 more
doaj   +1 more source

iPSYcare: the development of a linked electronic medical records database to study and optimize psychiatric care in Antwerp

BMC Research Notes, 2021
Objective The study of care trajectories of psychiatric patients across hospitals was previously not possible in Belgium as each hospital stores its data autonomously, and government-related registrations do not contain a unique identifier or are ...
Eva Rens, Joris Michielsen, Geert Dom, Roy Remmen, Kris Van den Broeck   +4 more
doaj   +1 more source

Psychiatric stigma in treatment seeking adults with personality problems: evidence from a sample of 214 patients.

Frontiers in Psychiatry, 2015
Stigmatization is a major hindrance in adult psychiatric patients with Axis-I diagnoses, as shown consistently in most studies. Significantly fewer studies on the emergence of psychiatric stigma in adult patients with personality disorders exist ...
Kirsten eCatthoor, Kirsten eCatthoor, Didier eSchrijvers, Didier eSchrijvers, Joost eHutsebaut, Dineke eFeenstra, Bernard eSabbe, Bernard eSabbe   +7 more
doaj   +1 more source

Abnormal emotion processing, but intact fairness and intentionality considerations during social decision making in schizophrenia.

Frontiers in Psychology, 2015
Schizophrenia is a severe mental disorder that is highly characterized by social cognitive impairments. Most studies investigating these impairments focus on one specific social domain such as emotion recognition.
Javier ede la Asuncion, Lise eDocx, Lise eDocx, Bernard eSabbe, Bernard eSabbe, Manuel eMorrens, Manuel eMorrens, Ellen eDe Bruijn   +7 more
doaj   +1 more source

DockQ: A Quality Measure for Protein-Protein Docking Models. [PDF]

PLoS ONE, 2016
The state-of-the-art to assess the structural quality of docking models is currently based on three related yet independent quality measures: Fnat, LRMS, and iRMS as proposed and standardized by CAPRI. These quality measures quantify different aspects of
Sankar Basu, Björn Wallner
doaj   +1 more source