Results 61 to 70 of about 470,765 (297)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Cross‐Sectional Study on Gastric Diseases and FGIDs in Bangladesh: Insights Into Causes, Symptoms, and Medications

Health Science Reports
Background and Aims Acute gastritis affects roughly 8 out of every 1000 people, while chronic gastritis affects about 2 out of every 10,000 people worldwide.
Md. Shoriful Islam, Rashni Agarwala, Sozoni Khatun, Tonima Enam, Ayesha Siddika, Tasfia Saffat, Mst. Israt Jahan, Afia Ibnath Shimki, Azifa Akter, Mahajabin Snigdha, Rubaia Tasmin   +10 more
doaj   +1 more source

Absence of Protein A Expression Is Associated With Higher Capsule Production in Staphylococcal Isolates

Frontiers in Microbiology, 2019
Staphylococcus aureus is a major human pathogen, and a leading cause of soft tissue and blood stream infections. One of the causes of its success as a pathogen is the peculiar array of immune evasion factors through which the bacterium avoids host ...
Tarcisio Brignoli, Tarcisio Brignoli, Andrea G. O. Manetti, Roberto Rosini, Andreas F. Haag, Andreas F. Haag, Vincenzo Scarlato, Fabio Bagnoli, Isabel Delany   +8 more
doaj   +1 more source

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis [PDF]

, 2011
Streptococcus suis is one of the most important pathogens in pigs and is also an emerging zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in meningitis, endocarditis and bronchopneumonia.
Smith, H.E., Smith, H E, H. E. Smith, R. Goethe, Rohde, Manfred, Valentin-Weigand, P., M. Rohde, Goethe, R, J. Willenborg, Willenborg, J, de Greeff, A, Goethe, R., Willenborg, J., A. de Greeff, Valentin-Weigand, P, De Greeff, A., Greeff, A., De, P. Valentin-Weigand, Fulde, M., M. Fulde, Fulde, M, Rohde, M.   +21 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread

Virulence, 2018
Invasive group A Streptococcus (iGAS) is frequently associated with emm1 isolates, with an attendant mortality of around 20%. Cases occasionally arise in previously healthy individuals with a history of upper respiratory tract infection, soft tissue ...
L. E. Lamb, M. K. Siggins, C. Scudamore, W. Macdonald, C. E. Turner, N. N. Lynskey, L. K. K. Tan, S. Sriskandan   +7 more
doaj   +1 more source

DEVELOPMENT OF COMPOSITION AND TECHNOLOGY OF CAPSULES WITH OIL OF VIBURNUM

Фармация и фармакология (Пятигорск), 2015
The article presents results of a study of excipients selection to create a capsule. We have presented an obtainment technology for the gelatin capsules with Viburnum oil.
A. V. Brazhenko, Y. V. Shikova, Z. R. Nova   +2 more
doaj   +1 more source

[American Capsule News, Number 402, November 30, 1963]

, 1963
American Capsule News, Number 402 published in Washington, D ...
American Capsule News
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source