Results 61 to 70 of about 318,398 (298)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Non-aqueous titrimetric assay of gabapentin in capsules using perchloric acid as titrant [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2011
Two simple, rapid, accurate and inexpensive methods using visual and potentiometric titrimetric techniques are described for the determination of gabapentin (GBP) in bulk drug as well as in capsules.
SAMEER A.M. ABDULRAHMAN, KANAKAPURA BASAVAIAH   +1 more
doaj  

The lens capsule [PDF]

Experimental Eye Research, 2009
The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype.
Brian P, Danysh, Melinda K, Duncan
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Flow of pH-responsive microcapsules in porous media [PDF]

, 2015
This article investigates the use micro-capsules, containing a gelling agent hydroxypropyl cellulose (HPC), to alter flow paths in porous media. The aim is to preferentially block-off high permeability regions, thereby diverting the flow into adjacent un-

core   +1 more source

Crosslinked agarose encapsulated sorbents resistant to steam sterilization. Preparation and mechanical properties [PDF]

, 1983
The application of agarose in hemoperfusion is hampered by the lack of a suitable sterilization method. A technique has been developed for the crosslinking of agarose encapsulated sorbents by the reaction with 1,3-dichloro-2-propanol (DCP) under strong ...
Brunner, de Koning, Holloway, Loesgen, Nisizawa, Ouwerkerk, Plotz, Rawer, Tijssen, Williams   +9 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pharmacokinetic and drug absorption profiles of the anti-hyperglycaemic agent gliclazide in oral tissue-targeted microcapsules in rats [PDF]

Scripta Medica, 2020
Background/Aim: Gliclazide is one of the most commonly prescribed oral anti-hyperglycaemic therapies in type 2 diabetes mellitus (T2D). Recently reported additional beneficial pharmacological properties of gliclazide, including immunomodulatory and ...
Jović Jelena, Milijašević Boris, Vukmirović Saša, Vasović Velibor, Mikov Momir, Mooranian Armin, Al-Salami Hani, Golocorbin-Kon Svetlana   +7 more
doaj  

Production of solid dosage forms of immunoglobulin products

Биопрепараты: Профилактика, диагностика, лечение, 2021
At the moment, there are no scientific publications devoted to the technological aspects of production of immunoglobulin solid dosage forms. The aim of the study was to review Russian and foreign literature on production of immunoglobulin solid dosage ...
E. G. Abramova, A. V. Komissarov, N. V. Sinitsyna, I. M. Zhulidov, A. K. Nikiforov   +4 more
doaj   +1 more source

AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells:Implications for age-associated fibrosis [PDF]

, 2016
Proteins in basement membrane (BM) are long-lived and accumulate chemical modifications during aging; advanced glycation end-product (AGE) formation is one such modification. The human lens capsule is a BM secreted by lens epithelial cells. In this study,
Glomb, Marcus, Gupta, Pankaj, Howell, Scott, Nagaraj, Ram, Raghavan, Cibin, Singh, Annapurna, Smith, Andrew, Smith, Dawn, Smuda, Mareen, Wormstone, Ian   +9 more
core   +1 more source