Results 211 to 220 of about 29,026 (312)

Development of a Next‐Generation Sequencing Protocol for Assessing Lenacapavir Resistance in HIV‐1 Capsid

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Lenacapavir (LEN) is a first‐in‐class capsid inhibitor (CAI) that targets multiple stages of the HIV‐1 lifecycle, showing efficacy in heavily treatment‐experienced (HTE) individuals with multidrug‐resistance (MDR) and in pre‐exposure prophylaxis (PrEP). This study aimed to characterize a novel in‐house next‐generation sequencing (NGS) protocol
Omar El Khalili   +10 more
wiley   +1 more source

How Middle Managers Affect Frontline Idea Generation: Evidence From Healthcare Operations

open access: yesJournal of Operations Management, Volume 72, Issue 1, Page 21-41, January 2026.
ABSTRACT This multiple case study develops a mid‐range theory on how frontline idea generation is affected by the actions of an organization's middle management. The study draws from four acute‐care hospitals in Germany and involves 36 semi‐structured interviews with representatives from all hierarchy levels.
Felix L. Mosner   +2 more
wiley   +1 more source

The Interplay of Multivalence and Amphiphilicity in Antimicrobial Bottle Brush Copolymers

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 2, 29 January 2026.
Antimicrobial polymers based on tert‐butyl acrylamide and aminoethyl acrylamide are varied in composition and architecture (bottle brush vs. linear copolymers). Linear copolymers show drastically increased selectivities, which is likely a result of differing self‐assembly behavior, as bottle brushes form strong intramolecular associations limiting ...
Anne‐Catherine Lehnen   +10 more
wiley   +1 more source

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