Results 131 to 140 of about 45,963 (197)

Estudo da cadeia produtiva do cará (dioscorea sp.) no município de Caapiranga/AM

open access: yes, 2011
No desenvolvimento da história da agricultura principalmente das olerícolas que hoje, circulam no mercado de Manaus e do Brasil, a grande maioria já foram fruto de domesticações, realizadas pelos povos indígenas, e uma variedade de planta hoje não ...
Paulo Henrique da Silva
core   +1 more source

Variant Class–Specific Phenotypes and Outcomes in Pediatric TBX4‐Associated Pulmonary Hypertension [PDF]

open access: yesPediatr Pulmonol
ABSTRACT Aim To describe the variant class associations with phenotype, natural history, treatment response, and outcomes in children with TBX4‐associated pulmonary hypertension (TBX4‐PH). Methods Retrospective cohort analysis of children < 18 years referred to the National Paediatric Pulmonary Hypertension Service between 2001 and 2025. Results Twenty‐
Morgan C   +12 more
europepmc   +2 more sources

Safety of Nonsteroidal Anti‐Inflammatory Drug Use in Traumatic Brain Injury

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 10, October 2026.
ABSTRACT Background Use of nonsteroidal anti‐inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14 days of TBI was associated with a clinically significant progression of intracranial bleed (PIB).
Jennifer Beavers   +10 more
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1717-1737, October 2026.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman   +3 more
wiley   +1 more source

Revertant Mosaicism Obscures Long‐Awaited Molecular Confirmation of Diamond‐Blackfan Anemia

open access: yes
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2381-2383, October 2026.
Nicholas A. Borja, Mustafa Tekin
wiley   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

open access: yesInternational Journal of Dermatology, Volume 65, Issue 10, Page 2038-2048, October 2026.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad   +2 more
wiley   +1 more source

Performance of Automated Hematology Analyzer Criteria in Detecting Peripheral Blood Smear Abnormalities: A Systematic Literature Review

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1008-1022, October 2026.
ABSTRACT Objectives Criteria for visual examination of stained peripheral blood smear (PBS) differ among institutions in the United States and internationally. In an effort to standardize review criteria, the International Consensus Group for Hematology Review (ICGHR) proposed in 2005 a consensus list of rules for CBC findings that should trigger a ...
Elizabeth L. Courville   +14 more
wiley   +1 more source

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