Results 191 to 200 of about 70,871 (233)

Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 841-855, May 2026.
This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin, Marie Tauber, Robert Sidbury, Jonathan I. Silverberg, Kim A. Papp, Diamant Thaçi, Marjolein S. De Bruin‐Weller, Adam Reich, Ketty Peris, Kirk Barber, Ryszard Galus, Andrzej Kaszuba, Matthew Zirwas, Walter K. Nahm, Gretel Trullenque, Laura Maintz, Sady Alpizar, Sang Wook Son, Vivian Laquer, Linda Stein Gold, Soo Yeon Cheong, Anna Ryzhkova, Agnes Drahos, Liliana Ulianov, Christophe Piketty   +24 more
wiley   +1 more source

Efficacy of an Oral Chondroprotective Joint Supplement on Stride Length and Gait Symmetry in Aged Geldings with Chronic Lameness. [PDF]

Animals (Basel)
Harbowy RM, Robison CI, Tillman I, Manfredi JM, Nielsen BD.   +4 more
europepmc   +1 more source

Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 856-866, May 2026.
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman‐Yassky, Mona Shahriari, Xinghua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D'Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy   +13 more
wiley   +1 more source

Effects of Isothermal Treatment on A_gZIF-62: Implications on Porosity, Separations, and Grain Boundary Defect Removal. [PDF]

Small Sci
Stone DM, Doherty CM, Acharya DP, Morgan SE, Abdelmigeed MO, Nguyen J, Harvey-Reid NC, Jangodaz E, Telfer SG, Parsons GN, Cowan MG.   +10 more
europepmc   +1 more source

Rapid improvement of itch with nemolizumab in atopic dermatitis and prurigo nodularis phase 3 studies

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 867-875, May 2026.
Achieving rapid control of itch in atopic dermatitis and prurigo nodularis may minimize symptomatology and disease burden. Analysis of clinical trials in atopic dermatitis and prurigo nodularis showed significantly more patients in nemolizumab versus placebo groups achieved a meaningful clinical response in itch within 48 h, and separation increased ...
Sonja Ständer, Sarina B. Elmariah, Shawn G. Kwatra, Gil Yosipovitch, Andrew E. Pink, Soo Yeon Cheong, Xiaoxiao Chen, Zarif K. Jabbar‐Lopez, Liliana Ulianov, Christophe Piketty, Jonathan I. Silverberg   +10 more
wiley   +1 more source

Action design research to develop an interactive dashboard to visualise and compare patient data from Irish general practice (CARA). [PDF]

BMJ Open
Vornhagen H, Garzón-Orjuela N, Stasiewicz K, Garcia Pereira A, Parveen S, Porwol L, Collins C, Blake C, Vellinga A.   +8 more
europepmc   +1 more source

Signatures of Radiation‐Induced Stress and Putative Selection on Immune Targets in Chornobyl Wolves

Molecular Ecology, Volume 35, Issue 9, May 2026.
ABSTRACT Investigating the physiological and evolutionary consequences of contaminant exposure in wild populations is critical for understanding long‐term ecological impacts of anthropogenic change. However, how and why species persist, even thrive, in highly contaminated regions in the absence of humans remains a topic of much debate.
Cara N. Love, Stacey L. Lance, Thomas G. Hinton, Nicolas Rochette, James C. Beasley, Dmitry Shamovich, Michael E. Byrne, Brian Nadel, Sarah C. Webster, Shane C. Campbell‐Staton   +9 more
wiley   +1 more source

Pro‐Vitamin A Biofortified Cavendish Banana: Trait Stability in the Field

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3327-3344, May 2026.
ABSTRACT Vitamin A deficiency (VAD), a major global health concern, has driven efforts to develop staple crops with enhanced pro‐vitamin A (pVA) content. Delivering meaningful nutritional benefits, however, requires technologies that maintain elevated carotenoid levels under field conditions. Previous proof‐of‐concept work demonstrated that pVA content
Jimmy M. Tindamanyire, Jacinta L. Watkins, Cara Mortimer, Bulukani Mlalazi, Jeff Daniells, Rob Harding, James L. Dale, Jean‐Yves Paul   +7 more
wiley   +1 more source

Smartphone-based App to Assess Diabetic Peripheral Neuropathy. [PDF]

J Diabetes Sci Technol
Adenekan RAG, Adenekan AE, Leung KK, Muppidi S, Sakamuri S, Tan M, Tsai SA, Osikomaiya M, Okamura AM, Nunez CM, Kim SH, Yoshida KT.   +11 more
europepmc   +1 more source

A review of topsoil governance for mining and agriculture in South Africa and abroad

Restoration Ecology, Volume 34, Issue S1, May 2026.
Topsoil is taken for granted as the dirt under our feet. Yet, humanity hinges on 15 cm of topsoil. As with potable water, topsoil is a natural resource we depend on daily. This review examines the chronological development of topsoil conservation through the governance of legal and other instruments since 1701. It highlights how topsoil is defined, its
Chrizette D. Neethling, Surina Esterhuyse, Pieter W. van Deventer, Suzanne J. Milton, Joh R. Henschel   +4 more
wiley   +1 more source