Results 191 to 200 of about 393,681 (269)

Quality of Life in CAR-T Cell Therapy. [PDF]

Hematol Rep
Alati C, Pitea M, Porto G, Policastro G, Bilardi E, Utano G, Giordano L, Sgarlata A, Delfino IM, Idato A, Santoro G, Canale FA, Naso V, Martino M.   +13 more
europepmc   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Chemical priming potentiates mesothelin-targeting chimeric antigen receptor-engineered NK-92 antitumor activity by improving tumor trafficking and cytotoxic killing dynamics. [PDF]

Front Immunol
Ryu KS, Park H, Maeng E, Lim JY, Cho D, Choi SH, Park KS.   +6 more
europepmc   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Fertility management and outcomes after CAR T-cell therapy: an international survey from the Cellular Therapy and Immunobiology working party of the European Society for Blood and Marrow Transplantation. [PDF]

EClinicalMedicine
Orofino G, Sánchez-Ortega I, Mota JS, Aroldi A, Castilla-Llorente C, Bigenwald C, Dalle JH, Yacouben K, Di Blasi R, Galli E, Grandage V, Palasciano A, Bacon L, Franke GN, Fandrei D, Merz M, George L, Lopez-Corral L, Hecker JS, Mannina D, Bramanti S, Martin Gonzalez JA, Martínez-Cibrian N, Petersen SL, Polgarova K, Protheroe R, Richardson D, Ram R, Elias S, von Tresckow B, Stölzel F, Streiss I, Vallet N, Knippenberg J, Tomas AA, Pagliuca S, Malard F, Kuball J, Ruggeri A.   +38 more
europepmc   +1 more source

Car health

BMJ, 1998
openaire   +4 more sources

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Novel CAR T cell blend targeting PDPN and GD2 to overcome glioblastoma heterogeneity. [PDF]

J Immunother Cancer
Hübner J, Alsalkini M, McFleder R, Toppeta F, Wagner J, Liguori R, Grams B, Meyer-Hofmann M, Diener L, Monoranu CM, Hagemann C, Ferrazzi F, Ip CW, Ernestus RI, Einsele H, Hudecek M, Löhr M, Nerreter T, Nickl V.   +18 more
europepmc   +1 more source