Results 11 to 20 of about 17,373,161 (316)

A Novel Shape-Adjustable Surface and Its Applications in Car Design

open access: yesApplied Sciences, 2019
In this paper, a new parameterized surface, termed SQ-Coons surface, is proposed according to the build mode of Coons patch. The surface is always interpolated to the boundary curves, and its shape details could be controlled by the shape parameters in ...
Fan Liu, Xiaomin Ji, Gang Hu, Jing Gao
doaj   +2 more sources

Mapping CAR T-Cell Design Space Using Agent-Based Models

open access: yesFrontiers in Molecular Biosciences, 2022
Chimeric antigen receptor (CAR) T-cell therapy shows promise for treating liquid cancers and increasingly for solid tumors as well. While potential design strategies exist to address translational challenges, including the lack of unique tumor antigens ...
Alexis N. Prybutok   +11 more
doaj   +2 more sources

A New Car Concept Developed with Stylistic Design Engineering (SDE)

open access: yesInventions, 2020
In this work, a structured design method, the Stylistic Design Engineering (SDE), is applied for the construction of a new minivan car, in particular a new city car, which we will call FIAT 600 Omega.
Giampiero Donnici   +6 more
doaj   +2 more sources

Road testing new CAR design strategies in multiple myeloma. [PDF]

open access: yesFront Immunol, 2022
A deeper understanding of basic immunology principles and advances in bioengineering have accelerated the mass production of genetically-reprogrammed T-cells as living drugs to treat human diseases.
Rana PS, Murphy EV, Kort J, Driscoll JJ.
europepmc   +2 more sources

CAR-T design: Elements and their synergistic function

open access: yesEBioMedicine, 2020
Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically approved CAR-T–cell therapies have significant clinical efficacy in treating CD19-positive B cell cancers ...
Jayapriya Jayaraman   +7 more
doaj   +2 more sources

Car Design and Car Usage [PDF]

open access: yesProceedings of the Institution of Automobile Engineers, 1919
A Plea for the fuller Appreciation by Car Designers of the limited mechanical Knowledge and engineering Sense of those who buy Cars, together with some Notes of a few Directions in which Design should Be modified with Advantage equally to Manufacturer and User
Edgar N. Duffield
openaire   +2 more sources

Feasibility of controlling CD38-CAR T cell activity with a Tet-on inducible CAR design. [PDF]

open access: yesPLoS One, 2018
Recent clinical advances with chimeric antigen receptor (CAR) T cells have led to the accelerated clinical approval of CD19-CARs to treat acute lymphoblastic leukemia.
Drent E   +6 more
europepmc   +2 more sources

Putting Up a Big Front: Car Design and Size Affect Road-Crossing Behaviour. [PDF]

open access: yesPLoS One, 2016
Previous research suggests that people tend to see faces in car fronts and that they attribute personality characteristics to car faces. In the present study we investigated whether car design influences pedestrian road-crossing behaviour.
Klatt WK, Chesham A, Lobmaier JS.
europepmc   +2 more sources

Design Guidelines for the Size and Length of Chinese Characters Displayed in the Intelligent Vehicle’s Central Console Interface

open access: yesInformation, 2021
In order to ensure the driver’s safe driving, the human–computer interaction interface of an intelligent vehicle needs to convey important information. The text is an important carrier of this kind of information.
Fang You   +4 more
doaj   +1 more source

IMPROVEMENT EVALUATION METHODOLOGY OF VEHICLE LOAD AND ENERGY EFFICIENCY [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2022
Problem. There was a need to expand the well-known concept of vehicle operational properties - fuel efficiency arose in connection with the advent of new alternative power plants (electric motors, flywheel engines, hybrid power plants, etc.), which ...
Mikhail Podrigalo   +6 more
doaj   +1 more source

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