Results 51 to 60 of about 164,480 (312)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
THE IMPROVEMENT OF THE ROLLING STOCK DESIGN FOR CONTAINERS TRANSPORTATION
Nauka ta progres transportu, 2009 In relation to development of container transportations the demand on the specialized rolling stock best adjusted for transportation of containers is sharply increased.
V. M. Bubnov +2 more
doaj
BioResources, 2016 A methodology is presented for the determination of elastic material properties on laminated and non-laminated decorative veneers of a variety of wood types.
Andreas Dietzel +2 more
doaj +1 more source
Design of a Toroidal Pressure Vessel of Carbon Fiber for Hydrogen Cars Using the Finite Element Method and Deep Learning [PDF]
, 2022 Victor Pazmiño +6 more
openalex +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
EXPERIMENTAL STUDIES OF PIVOTALLY CONNECTED CAR PLATFORM FOR LARGE-CAPACITY CONTAINERS MODEL 13-1839
Nauka ta progres transportu, 2009 The work is devoted to experimental researches of pre-production model of swing-joint platform. An amount and order of conducting the preliminary tests, combinations of the test loadings are considered. The locations of setting the sensors as well as the
V. M. Bubnov +2 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
CAR-T design: Elements and their synergistic function
EBioMedicine, 2020 Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically approved CAR-T–cell therapies have significant clinical efficacy in treating CD19-positive B cell cancers ...
Jayapriya Jayaraman +7 more
doaj +1 more source
DETERMINATION OF ECONOMIC EFFICIENCY OF CARRIAGE-PLATFORMS USE OF SECTION TYPE
Nauka ta progres transportu, 2010 The article is devoted the comparative analysis of charges for the complete life cycle of 80-foot carriageplatform and carriage-platform of sectional type on the example of two models of carriages-platforms for the containers produced by JSC “Azovmash ...
V. M. Bubnov +2 more
doaj
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source