Results 121 to 130 of about 4,557,318 (356)

The value of car ownership and use in the United States

open access: yesNature Sustainability, 2021
JoAnn Moody   +3 more
semanticscholar   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

An analysis of household transportation spending during the 2007-2009 US economic recession [PDF]

open access: yes, 2014
The recent economic recession in the United States led to widespread destruction of jobs, home foreclosures, credit freeze and to creditor repossessions of key assets such as personal cars. Our objective is to empirically assess transportation conditions
Mallon-Keita, Yaye   +1 more
core  

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

How important are household demographic characteristics to explain private car use patterns? A multilevel approach to Austrian data [PDF]

open access: yes
Private car use is one of the major contributors to pollution in industrialised countries. It is therefore important to understand the factors that determine the demand for car use.
Alexia Fürnkranz-Prskawetz   +2 more
core  

Divergent Responses of Bacterial Communities to Permafrost Degradation and Their Associations With Carbon Across Vertical Profiles

open access: yesAdvanced Science, EarlyView.
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen   +13 more
wiley   +1 more source

On the Road to Self-Sufficiency after Welfare Reform: An Assessment of the Impact of Changes in Welfare Asset Limits on Auto- Ownership Rates and Employment [PDF]

open access: yes
In this paper, we assess the impact of the easing of vehicle exemption limits and asset restrictions after the passage of welfare reform legislation on the rates of car-ownership observed among female headed households with children. Prior to the passage
Cynthia Bansak   +2 more
core  

Car pride and its bidirectional relations with car ownership: Case studies in New York City and Houston

open access: yesTransportation Research Part A: Policy and Practice, 2019
The car fulfills not only instrumental transportation functions, but also holds important symbolic and affective meaning for its owners and users. In particular, owning and using a car can be a symbol of an individual’s social status or personal image ...
JoAnn Moody, Jinhuan Zhao
semanticscholar   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

open access: yesAdvanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu   +11 more
wiley   +1 more source

Car Ownership and Mode of Transport to Work in Ireland [PDF]

open access: yes
Rapid economic and demographic change in Ireland over the last decade, with associated increases in car dependence and congestion, has focused policy on encouraging more sustainable forms of travel.
Anne Nolan, Nicola Commins
core  

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