Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tela de carbón activo: biomateriales para la proliferación y diferenciación de células mesenquimales [PDF]
[ES] Las fibras de carbón activo son materiales biocompatibles sobre los que las células pueden adherirse y proliferar. La adhesión de las células vivas sobre el carbón activo incluye, en primera aproximación, un fenómeno de adsorción que tiene lugar ...
Ruiz de Almodóvar, José Mariano +11 more
core
Technologies and perspectives for achieving carbon neutrality
Global development has been heavily reliant on the overexploitation of natural resources since the Industrial Revolution. With the extensive use of fossil fuels, deforestation, and other forms of land-use change, anthropogenic activities have contributed
Fang Wang +57 more
semanticscholar +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Geles de carbón de origen natural [PDF]
[EN] Most carbon gels investigated so far and reported in the literature were prepared from resorcinol crosslinked with formaldehyde in water, and were generally dried with supercritical CO2 before being pyrolysed. In the present paper, through some
Pizzi, A. +8 more
core
Combustión de carbón vegetal, enemigo latente del medio ambiente
El presente artículo emerge de una investigación, la cual se plantea como objetivo generar una estrategia medio ambiental que permita minimizar el impacto de la calidad del aire producida por la combustión del carbón vegetal en la población de Barrio ...
Mary Lucero Valencia Cuero
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
En torno al proteccionismo hullero: notas a unas lecturas [PDF]
Publicad
Sudriá, Carles
core +2 more sources
La productividad industrial y el conflicto entre el capital y el trabajo en la Argentina setentista : Una reconsideración en perspectiva [PDF]
Fil: Carbón, Leandro. Universidad de Buenos Aires; Argentina.Fil: Carbón, Leandro. Universidad Nacional Arturo Jauretche; Argentina.Fil: Marini, Mariela. Universidad de Buenos Aires; Argentina.Fil: Marini, Mariela.
Carbón, Leandro, Marini, Mariela
core +1 more source
Synthetic Carbons Derived from a Styrene—Divinylbenzene Copolymer Using Phosphoric Acid Activation
Activated carbons were obtained by phosphoric acid activation of a porous chloromethylated and sulphonated styrene—divinylbenzene copolymer in two different atmospheres (argon and air) at various temperatures in the range 400–1000°C. The development with
A.M. Puziy +4 more
doaj +1 more source

