Results 301 to 310 of about 120,317 (381)

Identification of a Second‐Hit Brain Somatic DEPDC5 Variant Supports Causality of a DEPDC5 Germline Variant of Uncertain Significance. Time for a Classification Update?

American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Germline variants in DEPDC5 are a cause of familial focal epilepsy with variable foci. Affected individuals may have focal cortical dysplasia if a second brain somatic variant occurs. As access to brain tissue is limited, the second somatic hit in the brain is usually presumed if a clear pathogenic germline variant is present. Here, we present
Ala'a Alsayed, Zainab Hakim, Daria Merrikh, Maryam Khanbabaei, Navprabhjot Kaur, Walter Hader, Tyler Soule, Setareh Ashtiani, Grace Polanco‐Tovar, Morris Scantlebury, Hamed Rahi, Yang Cao, Jennifer A. Chan, Juan P. Appendino, Gerald Pfeffer, Ping Yee Billie Au, Karl Martin Klein   +16 more
wiley   +1 more source

Synergistic sonocatalytic degradation of carbamazepine and 17α-ethinylestradiol in the presence of carbon nanotube yarn. [PDF]

Ultrason Sonochem
Choi JS, Kim HH, Lingamdinne LP, Koduru JR, Chang YY, Gihm SH, Jang M, Park CM, Yoon Y.   +8 more
europepmc   +1 more source

Safety and Efficacy of Eslicarbazepine Acetate in Children Diagnosed With a Focal Seizure Disorder: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 12, December 2025.
ABSTRACT Background Epilepsy can have a negative impact on cognitive and social functioning. Eslicarbazepine acetate (ESL) is used to treat focal seizures, although its safety and efficacy, particularly as an additional treatment, warrant more study.
Neha Bhagwan Das, Muhammad Zain Ul Haq, Eiman Anwar, Manav Das, Ariba Asif, Umaimah Naeem, Mohammad Mohsin Khan, Mahrukh Arshad, Saima Javed, Aymar Akilimali   +9 more
wiley   +1 more source

Sensitivity of Tepotinib to Inhibitors or Inducers of CYP3A4 and P-Gp: Drug Interaction Studies and Physiologically-Based Pharmacokinetic Analysis. [PDF]

Clin Transl Sci
Strotmann R, Lüpfert C, Krebs-Brown A, Ke A, Boedding M, Heuer J, Yeo KR, Benincosa L, Venkatakrishnan K.   +8 more
europepmc   +1 more source

Uptake and metabolism of the antiepileptic drug carbamazepine in plants and role of endophytic bacteria

, 2017
André Laurent Sauvêtre
openalex   +1 more source

Paliperidone‐Induced Catatonia: Case Series and Review of Literature

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Paliperidone, a second‐generation antipsychotic commonly used to treat schizophrenia and schizoaffective disorder, has been rarely associated with inducing catatonia, a severe neuropsychiatric syndrome characterized by motor disturbances and altered mental status.
Sikandar Saeed, Sakshi Prasad, Arham Javaid, Elzar Matmusaeva, Marcos Rocha, Resha Karani, Samkit Jain, Khai Tran, Sasidhar Gunturu   +8 more
wiley   +1 more source

Ferulic Acid Attenuates Seizure Severity and Enhances Valproate and Carbamazepine Seizure Preventing Efficacy by Regulating Hippocampal Interleukin-1β Level and Antioxidant Capacity in Mice. [PDF]

Oxid Med Cell Longev
Taheri E, Hassanpourezatti M.
europepmc   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

The Canadian Journal of Chemical Engineering, Volume 103, Issue 12, Page 5812-5818, December 2025.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou, Georgia Gatidou, Athanasios S. Stasinakis, Michail S. Fountoulakis   +3 more
wiley   +1 more source