Results 321 to 330 of about 120,317 (381)
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Activation of T cells by carbamazepine and carbamazepine metabolites

Journal of Allergy and Clinical Immunology, 2006
T-cell-mediated hypersensitivity is a rare but serious manifestation of drug therapy.To explore the mechanisms of drug presentation to T cells and the possibility that generation of metabolite-specific T cells may provoke cross-sensitization between drugs.A lymphocyte transformation test was performed on 13 hypersensitive patients with carbamazepine ...
Ying, Wu   +12 more
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Carbamazepine and the lung

European Respiratory Journal, 1990
A 69 yr old man was admitted with a 10 day history of fever, arthromyalgia, dyspnoea, dry cough and pleuritic pain. Temperature was 38 degrees C; tachypnoea 36 rpm. Extensive crackles were audible over both upper lung fields. Chest X-ray showed bilateral alveolar infiltrates.
B, Barreiro, F, Manresa, J, Valldeperas
openaire   +2 more sources

The pharmacokinetics of carbamazepine

European Journal of Clinical Pharmacology, 1977
The time-courses of plasma carbamazepine concentrations were followed in six apparently healthy adult subjects who, at different times, took single oral drug doses of 200, 400, 500, 600, 700, 800 and 900 mg. There were some suggestions of impaired bioavailability of the drug when given in tablet form.
L M, Cotter   +5 more
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Carbamazepine adverse drug reactions

Expert Review of Clinical Pharmacology, 2018
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ can negatively impact the quality of life of patients, as well as increase health ...
I. Fricke-Galindo   +3 more
semanticscholar   +1 more source

In vitro embryotoxicity of carbamazepine and carbamazepine-10,11-epoxide

Teratology, 1996
Carbamazepine (Tegretol, CBZ) is an anticonvulsant drug that is very effective in the treatment of tonic-clonic seizures and is gaining acceptance as a treatment for various psychiatric disorders. The drug is embryotoxic in rodents and has been reported to produce neural tube defects in approximated 1% of prenatally exposed human offspring.
D K, Hansen   +3 more
openaire   +2 more sources

Carbamazepine in Dementia

Journal of Clinical Psychopharmacology, 1986
Dementia is an ailment that is becoming a major management problem. The presentations of dementias vary depending upon the site of lesions and their severity. Different medications have been tried to relieve some of the more common symptoms associated with the dementias.
openaire   +2 more sources

Carbamazepine

2016
This chapter includes the aspects of carbamazepine. The drug is synthesized by the use of 5H-dibenz[b,f]azepine and phosgene followed by subsequent reaction with ammonia. Carbamazepine is generally used for the treatment of seizure disorders and neuropathic pain, it is also important as off-label for a second-line treatment for bipolar disorder and in ...
openaire   +2 more sources

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