Results 171 to 180 of about 1,591 (256)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Sustainable Polymer Biocomposites for Food Packaging: Green Nanotechnology, Circular Plastic Upcycling and Smart Functional Materials

Packaging Technology and Science, EarlyView.
Graphical abstract showing the development of biodegradable polymer biocomposites reinforced with natural fibres, green nanoparticles and waste‐plastic upcycling pathways toward sustainable smart food packaging materials ABSTRACT The fundamental hypothesis behind this review is that the combination of biodegradable polymer‐based biocomposites, which ...
Chandra Sekhar Espenti, Jaewoong Lee
wiley   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

Small Methods, EarlyView.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun, Isabella Vasquez, Hannah Bowman, Robert Posey, Zhongkui Hong, Joshua Tropp, Indrajit Srivastava   +6 more
wiley   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

The Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros, Livia C. L. Valente, Thiago Barcellos, Daniela Hartwig, Laura Abenante, Eder J. Lenardão   +5 more
wiley   +1 more source

Multielemental Analysis in Rice Grains by Total Reflection X‐Ray Fluorescence

X-Ray Spectrometry, EarlyView.
ABSTRACT Rice (Oryza sativa) is a staple food cultivated worldwide and represents a significant source of essential nutrients for humans. However, this cereal may also contain potentially toxic elements including chromium, arsenic, and lead typically present at trace concentrations (ng.g−1).
F. T. S. Tsuyama, R. G. Leitão, C. G. L. Canellas, G. C. Ferreira, J. L. Pereira, R. S. Santos, J. T. Assis, D. F. Oliveira, M. J. Anjos   +8 more
wiley   +1 more source

Surface Roughness of Different Composite Resins after Application of 15% Carbamide Peroxide and Brushing with Toothpaste: An In-Vitro Study. [PDF]

Front Dent, 2019
Navimipour EJ, Ajami AA, Oskoee SS, Kahnamou MA, Bahari M, Ebrahimi Chaharom ME, Shojaei SM.   +6 more
europepmc   +1 more source

Surface Micro‐Discharge Plasma for Multiple Teeth Bleaching: Efficacy, Mechanism and Safety

High Voltage, EarlyView.
ABSTRACT Hydrogen peroxide (H2O2) is the commonly‐used bleaching chemical in clinical practice, but its excessive concentrations can cause tooth damage. Atmospheric pressure cold plasma is considered a promising new technique for tooth bleaching. Surface micro‐discharge (SMD) devices can generate large‐scale plasma, which holds potential for treating ...
Ruike Chen, Haoran Feng, Yinglong Li, Hong Pan, Hangbo Xu, Zhen Jiao, Dongjie Cui, Ruonan Ma   +7 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

High-concentration carbamide peroxide can reduce the sensitivity caused by in-office tooth bleaching: a single-blinded randomized controlled trial. [PDF]

J Appl Oral Sci, 2018
Peixoto AC, Vaez SC, Pereira NAR, Santana CNDS, Soares KDA, Romão ACTR, Ferreira LF, Martins-Filho PRS, Faria-E-Silva AL.   +8 more
europepmc   +1 more source