Results 231 to 240 of about 5,020 (299)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Effect of different concentrations of carbamide peroxide on the staining susceptibility of resin composites.

J Conserv Dent, 2018
Esmaeili B, Zenouz GA, Khazaei F, Daryakenari G, Bizhani A.   +4 more
europepmc   +1 more source

Periodontitis and high phosphate intake alone or in combination adversely affect the kidney

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis and high phosphate (HP) intake can negatively affect the kidney in the presence of renal disease. This study aimed to evaluate the effects of periodontitis or HP intake, either alone or concurrently, on the periodontal tissue and the kidney under normal renal conditions.
Ae Ri Kim, Min Seo Kim, Jiwon Seo, Eun‐Jung Bak, Yun‐Jung Yoo   +4 more
wiley   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Chitosan‐induced modulation of secondary metabolism and stress tolerance in Salvia rosmarinus under combined drought and heat stress

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abiotic stresses, particularly drought and elevated temperatures, negatively affect plant physiological and metabolic processes. This study investigated the effects of drought, heat, and combined stress on Salvia rosmarinus (rosemary), and evaluated foliar‐applied chitosan as a biostimulant.
Inês Mansinhos, Sandra Gonçalves, Raquel Rodríguez‐Solana, Efrén Pérez‐Santín, María I Fernández‐Marín, Emma Cantos‐Villar, Anabela Romano   +6 more
wiley   +1 more source

In-office tooth bleaching protocols: an umbrella review of systematic reviews and meta-analyses on whitening efficacy and tooth sensitivity. [PDF]

Saudi Dent J
Hajeer O, Hasan A.
europepmc   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Phthalimidoperoxycaproic Acid (PAP) Versus Peroxides and Impact on Dental Enamel After Whitening Treatment: An In Vitro Study. [PDF]

J Funct Biomater
Llena C, Saenz L, Ghilotti J, Folguera S, Melo M.   +4 more
europepmc   +1 more source