Results 81 to 90 of about 17,995 (248)
Movement Disorders Clinical Practice, EarlyView.
Juliana dos Santos Duarte +3 more
wiley +1 more source
Subcutaneous Levodopa in Parkinson's Disease: A Systematic Review and Meta‐Analysis
ABSTRACT Background Many Parkinson's disease patients receiving oral levodopa/carbidopa experience a troublesome wearing off effect. Higher doses to mitigate OFF‐time are limited by adverse effects occurring at peak dopamine levels, particularly dyskinesia.
Matthew Burton +6 more
wiley +1 more source
Levodopa/carbidopa intesztinális gél alkalmazása előrehaladott Parkinson-kórban. [PDF]
Parkinson's disease is the second most common neurodegenerative disorder around the world. Levodopa has remained the "gold standard" of the therapy even several decades after its introduction.
Bereczki, Dániel +4 more
core
Deep Brain Stimulation for Parkinson's Disease with Early Motor Complications:A UK Cost-Effectiveness Analysis [PDF]
International audienceBackground: Parkinson’s disease (PD) is a debilitating illness associated with considerable impairment of quality of life and substantial costs to health care systems.
Eldridge, Paul R. +7 more
core +9 more sources
Refractory Motor Complications: Towards a Pragmatic Definition
Movement Disorders Clinical Practice, EarlyView.
Georg Ebersbach, Tobias Warnecke
wiley +1 more source
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Enfermedad de Parkinson avanzada. Características clínicas y tratamiento. Parte II
Resumen: Introducción: Muchos de los pacientes con enfermedad de Parkinson (EP) presentan al cabo de varios años fluctuaciones y discinesias graves que requieren de terapias algo más agresivas como la estimulación cerebral profunda del núcleo ...
J. Kulisevsky +15 more
doaj +1 more source
Abstract Background Dyskinesia is a debilitating complication of dopaminergic therapy in advanced Parkinson's disease. Objectives To evaluate the effect of levodopa‐carbidopa intestinal gel (LCIG) on dyskinesia burden. Methods This is a post hoc analysis of the retrospective, observational COmedication Study assessing Mono‐ and cOmbination therapy with
Alfonso Fasano +11 more
wiley +1 more source
Efficacy and Safety of Foslevodopa/Foscarbidopa Monotherapy in Patients with Parkinson's Disease
Abstract Background As Parkinson's disease (PD) progresses, managing symptoms becomes increasingly difficult. Foslevodopa/foscarbidopa (LDp/CDp), a 24‐hour/day continuous subcutaneous infusion of levodopa/carbidopa (LD/CD) prodrugs, improves motor complications.
Jason Aldred +11 more
wiley +1 more source

