Results 101 to 110 of about 132,531 (238)

Antibacterial and Carbohydrate Digestive Enzyme Inhibitory Effects of Native Plants Used for Medicinal and Culinary Purposes in Cyprus

open access: yesNatural Product Communications
Natural products are an inexhaustive reservoir of bioactive compounds with diverse effects protecting human health as components of nutrition and as active substances of drugs.
Atalanti Christou   +4 more
doaj   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

A General Enzymatic Strategy for Site‐Specific Incorporation of Modified Genetic Building Blocks Into DNA

open access: yesAdvanced Science, EarlyView.
Eco‐friendly enzymatic synthesis of high‐fidelity, site‐specifically modified DNA using 3′‐blocked nucleotides for full synthetic control and next‐generation sequencing compatibility. ABSTRACT Methods for site‐specific incorporation of modified DNA building blocks remain limited.
Raveena Raveena   +2 more
wiley   +1 more source

Metagenomic and culture-dependent analysis of Rhinopithecius bieti gut microbiota and characterization of a novel genus of Sphingobacteriaceae

open access: yesScientific Reports
Culture-dependent and metagenomic binning techniques were employed to gain an insight into the diversification of gut bacteria in Rhinopithecius bieti, a highly endangered primate endemic to China.
Qiong Wang   +3 more
doaj   +1 more source

In vitro and in silico investigation of the multifunctional bioactivity of the lichen Oxneriopsis bassiae (Ach.) S.Y. Kondr., Upreti & Hur

open access: yesResults in Chemistry
Lichens are recognized as rich sources of structurally diverse secondary metabolites with significant pharmacological potential. Several lichen-derived compounds exhibit antioxidant and enzyme inhibitory activities, particularly against carbohydrate ...
Naincy   +4 more
doaj   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

open access: yesAdvanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li   +7 more
wiley   +1 more source

Alteration in Hepatic Enzyme Activity of Tilapia mossambica upon Exposure to Fluoride

open access: yesRADS Journal of Biological Research & Applied Science, 2018
Fluoride, as the super reactive element fluorine, is found naturally throughout earth's crust. It has been identified as a strong, persistent powerful cumulative toxic agent, commonly distributed in the rivers, lakes, seas of earth.
Farha Aziz   +2 more
doaj  

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

open access: yesAdvanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru   +6 more
wiley   +1 more source

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