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Enzyme promiscuity of carbohydrate active enzymes and their applications in biocatalysis.
Current Opinion in Structural Biology, 2020The application of biocatalysis for the synthesis of glycans and glycoconjugates is a well-established and successful strategy, both for small and large scale synthesis.
Edward G. Pallister, C. Gray, S. Flitsch
semanticscholar +3 more sources
Carbohydrate-active enzymes (CAZymes) in the gut microbiome
Nature Reviews Microbiology, 2022The 1013-1014 microorganisms present in the human gut (collectively known as the human gut microbiota) dedicate substantial percentages of their genomes to the degradation and uptake of carbohydrates, indicating the importance of this class of molecules.
Stephen Withers +2 more
exaly +3 more sources
Role of carbohydrate-active enzymes in mycorrhizal symbioses
Essays in Biochemistry, 2023Abstract Mycorrhizal fungi form mutually beneficial interactions with a wide range of terrestrial plants. During this symbiosis, the associated fungus provides mineral nutrients, such as phosphorus and nitrogen, to its host plant in exchange of photosynthesis-derived carbohydrates.
Gong, Yuhua +3 more
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Journal of Biological Chemistry, 2015 Carbohydrate-active enzymes have multiple biological roles and industrial applications. Advances in genome and transcriptome sequencing together with associated bioinformatics tools have identified vast numbers of putative carbohydrate-degrading and ...
Julia Schückel +2 more
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Analytical Chemistry, 2011 International audienceWe report here the development of a straightforward, sensitive, and quantitative NMR-based method for high-throughput characterization of carbohydrate structure and screening of carbohydrate active enzyme (CAZyme) specificity ...
Romain Irague +8 more
semanticscholar +2 more sources
Advances in the understanding and exploitation of carbohydrate-active enzymes
Current Opinion in Chemical BiologyCarbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modification and degradation of all glycans in Nature. Advances in genomic and metagenomic methodologies, in conjunction with lower cost gene synthesis, have provided access to a steady stream of new CAZymes with both well-established and novel mechanisms.
Stephen Withers +2 more
exaly +3 more sources