Comparative Insights into Digestion and Gut Microbiota Modulation of Polysaccharides from Ginseng, Ganoderma lucidum, and Dendrobium officinale. [PDF]
Pan X +7 more
europepmc +1 more source
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
Postprandial response of leptin and adiponectin to standardized high-carbohydrate and high-fat meals in adults: A cross-sectional study. [PDF]
Del Razo-Olvera FM +14 more
europepmc +1 more source
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi +14 more
wiley +1 more source
Dietary pollen and carbohydrate sources influence longevity, physiology, and gut microbiota in honey bee (Apis mellifera). [PDF]
Najarpoor A, Namin SM, Ghosh S, Jung C.
europepmc +1 more source
Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang +8 more
wiley +1 more source
Effects of Different Feeding Regimes on Rumen Microbial Composition, Functional Potential, and Fermentation Characteristics of Longdong Goats (<i>Capra hircus</i>). [PDF]
Wang K +5 more
europepmc +1 more source
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source
Genome association of carbohydrate metabolites provides new insights toward functional breeding in coffee. [PDF]
Tavares Flores E +9 more
europepmc +1 more source
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi +8 more
wiley +1 more source

