Results 1 to 10 of about 13,357 (204)
Journal of Immunology Research, 2022 Aims/Hypothesis. The role of microRNAs (miRNAs) in type 1 diabetes (T1D) pathogenesis and progression has been described but remains elusive. Objectives. To evaluate the potential biological involvement of miRNA expression in the immune response and beta
Aritania Sousa Santos +7 more
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Variant rs17619600 in the gene encoding serotonin receptor 2B (HTR2B) increases the risk of gestational diabetes mellitus: a case–control study [PDF]
European Journal of Medical Research, 2023 Background During pregnancy, the increase in maternal insulin resistance is compensated by hyperplasia and increased function of maternal pancreatic beta cells; the failure of this compensatory mechanism is associated with gestational diabetes mellitus ...
Juliana Regina Chamlian Zucare Penno +7 more
doaj +2 more sources
Mediators of Inflammation, 2020 Background and Aims. Since hyperglycemia promotes inflammation by different pathways and inflammation participates in the development of chronic diabetes complications, we investigated the association between the leukotriene (LT) pathway and ...
Daniele P. Santos-Bezerra +10 more
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MicroRNAs modulated by DPP-4 inhibitor and bedtime NPH insulin therapy in individuals with type 2 diabetes [PDF]
Frontiers in EndocrinologyBackgroundMicroRNAs (miRNAs) and their target genes can elucidate mechanisms of drug action and serve as potential therapeutic biomarkers.MethodsTo evaluate the effects of bedtime NPH insulin and sitagliptin on serum miRNA expression in individuals with ...
Aritania Sousa Santos +3 more
doaj +2 more sources
Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals [PDF]
Frontiers in EndocrinologyAimThe pathogenesis of chronic diabetes complications has oxidative stress as one of the major elements, and single-nucleotide polymorphisms (SNPs) in genes belonging to antioxidant pathways modulate susceptibility to these complications.
Gustavo Daher +11 more
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Diabetology & Metabolic Syndrome, 2023 Introduction Diabetes mellitus (DM) is associated with severe forms of COVID-19 but little is known about the diabetes—related phenotype considering pre-admission, on-admission and data covering the entire hospitalization period.
Lais Isidoro Alves +6 more
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Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans
Scientific Reports, 2017 There is a scarcity of data of zinc transporter-8 autoantibody (ZnT8A) on mixed populations such as Brazilian. Therefore, we evaluated the relevance of ZnT8A for type 1 diabetes (T1D) diagnosis and the role of ZnT8 coding gene (SLC30A8) in T1D ...
Karla Fabiana Brasil Gomes +7 more
doaj +1 more source
Frontiers in Endocrinology, 2019 Objective: To compare the serum micro-RNAs (miRNAs) profile of individuals with type 1 diabetes without microvascular complications vs. those with multiple severe microvascular complications, in order to identify epigenetically modulated pathways in ...
Daniele P. Santos-Bezerra +13 more
doaj +1 more source
Análise bioquímica de calos de pinhão-manso Biochemical analysis of callus from physic nut
Ciência Rural, 2010 O pinhão-manso (Jatropha curcas L.) vem ganhando importância por seu potencial como insumo ao biodiesel. Estudos visam à adequação agronômica e a cultura de tecidos contribui indiretamente com este aspecto, auxiliando em pesquisas aplicadas como em ...
Dalilhia Nazaré dos Santos +5 more
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Isolamento de lectinas por cromatografia de afinidade
Revista de Investigación Agraria y Ambiental, 2017 Cromatografia de afinidade é uma técnica usada para separar compostos, como, por exemplo, determinadas proteínas, que têm a capacidade de se ligar não covalentemente e reversivelmente a moléculas específicas conhecidas como ligantes.
José Camilo Torres Romero +3 more
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