Results 1 to 10 of about 2,065 (121)
Journal of Immunology Research, 2022 Aims/Hypothesis. The role of microRNAs (miRNAs) in type 1 diabetes (T1D) pathogenesis and progression has been described but remains elusive. Objectives. To evaluate the potential biological involvement of miRNA expression in the immune response and beta
Aritania Sousa Santos +7 more
doaj +2 more sources
Mediators of Inflammation, 2020 Background and Aims. Since hyperglycemia promotes inflammation by different pathways and inflammation participates in the development of chronic diabetes complications, we investigated the association between the leukotriene (LT) pathway and ...
Daniele P. Santos-Bezerra +10 more
doaj +2 more sources
Variant rs17619600 in the gene encoding serotonin receptor 2B (HTR2B) increases the risk of gestational diabetes mellitus: a case–control study [PDF]
European Journal of Medical Research, 2023 Background During pregnancy, the increase in maternal insulin resistance is compensated by hyperplasia and increased function of maternal pancreatic beta cells; the failure of this compensatory mechanism is associated with gestational diabetes mellitus ...
Juliana Regina Chamlian Zucare Penno +7 more
doaj +2 more sources
MicroRNAs modulated by DPP-4 inhibitor and bedtime NPH insulin therapy in individuals with type 2 diabetes [PDF]
Frontiers in EndocrinologyBackgroundMicroRNAs (miRNAs) and their target genes can elucidate mechanisms of drug action and serve as potential therapeutic biomarkers.MethodsTo evaluate the effects of bedtime NPH insulin and sitagliptin on serum miRNA expression in individuals with ...
Aritania Sousa Santos +3 more
doaj +2 more sources
Mediators of Inflammation, 2014 CD226 rs763361 variant increases susceptibility to type 1 diabetes (T1D) in Caucasians. There is no data about CD226 variants in the very heterogeneous Brazilian population bearing a wide degree of admixture. We investigated its association with T1D susceptibility, clinical phenotypes, and autoimmune manifestations (islet and extrapancreatic ...
Teresa Cristina Colvara Mattana +7 more
doaj +2 more sources
Carbohydrate Counting as a Precision Method for Glycemic Control in Youth With Type 1 Diabetes: A Systematic Review and Meta-Analysis. [PDF]
Int J PediatrBackground Although carbohydrate counting is a recommended method for managing diabetes, it is not widely used by patients with Type 1 diabetes mellitus. Aiming to emphasize the importance of this method, this study is aimed at quantitatively assessing the effectiveness of carbohydrate counting in reducing HbA1c levels in children and adolescents with ...
Guarçoni PV +3 more
europepmc +2 more sources
Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals [PDF]
Frontiers in EndocrinologyAimThe pathogenesis of chronic diabetes complications has oxidative stress as one of the major elements, and single-nucleotide polymorphisms (SNPs) in genes belonging to antioxidant pathways modulate susceptibility to these complications.
Gustavo Daher +11 more
doaj +2 more sources
Diabetology & Metabolic Syndrome, 2023 Introduction Diabetes mellitus (DM) is associated with severe forms of COVID-19 but little is known about the diabetes—related phenotype considering pre-admission, on-admission and data covering the entire hospitalization period.
Lais Isidoro Alves +6 more
doaj +1 more source
Functional Ecology, Volume 36, Issue 2, Page 341-355, February 2022., 2022 A free Plain Language Summary can be found within the Supporting Information of this article. Abstract Tropical tree species span a range of life‐history strategies within a fast–slow continuum. The position of a species within this continuum is thought to reflect a negative relationship between growth and storage, with fast‐growing species allocating ...
Caroline Signori‐Müller +19 more
wiley +1 more source
Veterinary Dermatology, Volume 31, Issue 6, Page 439-e116, December 2020., 2020 Background It has been demonstrated recently that immunoglobulin (Ig)E specific for cross‐reactive carbohydrate determinants (CCD) is present in the serum of allergen‐sensitized dogs and cats, and that these CCD‐specific antibodies might confound serological testing. Hypothesis/Objective The objective was to document the prevalence of CCD detectable in
Kenneth W. Lee +3 more
wiley +1 more source