Results 31 to 40 of about 1,419,333 (268)

Art Perception in the Museum: How We Spend Time and Space in Art Exhibitions

open access: yesi-Perception, 2017
Aesthetics research aiming at understanding art experience is an emerging field; however, most research is conducted in labs without access to real artworks, without the social context of a museum and without the presence of other persons.
Claus-Christian Carbon
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Predicting Preferences for Innovative Design: The “Repeated Evaluation Technique” (RET)

open access: yesGfK Marketing Intelligence Review, 2015
How do you realistically assess the success potential of innovative products? This task is quite challenging because the Average Joe generally has an aversion to innovation.
Carbon Claus-Christian
doaj   +1 more source

Design of Carbon–Carbon Ylides

open access: yesAngewandte Chemie
Abstract Here, we have reported the computational design of a new class of ylides, elusive carbon–carbon ylides featuring zwitterionic σ‐bonds, derived from the norbornane‐2,6‐dione framework. Utilizing the state‐of‐the‐art computational methods, we have demonstrated that appropriate substitutions on this scaffold
Muhammad Yasir Mehboob   +3 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Zeus Theopomenos and Theopoma (“Divine Drink (of Water)”?)

open access: yesGephyra
In this journal, V. Sauer and E. Olshausen (Sauer - Olshausen, Gephyra, 29, 2025, 56 no. 2) have recently published an interesting Imperial-period dedication (“Votiv- oder Weihinschrift eines Altar”) to a deity which they were not able to identify ...
Jan-mathieu Carbon
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Cognitive Mechanisms for Explaining Dynamics of Aesthetic Appreciation

open access: yesi-Perception, 2011
For many domains aesthetic appreciation has proven to be highly reliable. Evaluations of facial attractiveness, for instance, show high internal consistencies and impressively high inter-rater reliabilities, even across cultures.
Claus-Christian Carbon
doaj   +1 more source

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