Results 61 to 70 of about 3,356,168 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Factors driving carbon accumulation in forest biomass and soil organic carbon across natural forests and planted forests in China

open access: yesFrontiers in Forests and Global Change
IntroductionForests play a pivotal role within the global carbon cycle. However, how to enhance carbon storage in existing forests remains unclear.MethodsIn this study, we conduct a comprehensive analysis of data from 2,948 forest sites across China ...
Tao Wang, Lingbo Dong, Zhaogang Liu
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Organic carbon accumulation rates and nitrogen isotope ratios of ODP Site 172-1058

open access: yes, 2019
Organic carbon accumulation rates and nitrogen isotope ratios of ODP Site 172 ...
Thunell, Robert C   +5 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The Nordic Seas carbon budget: Sources, sinks, and uncertainties [PDF]

open access: yes, 2011
A carbon budget for the Nordic Seas is derived by combining recent inorganic carbon data from the CARINA database with relevant volume transports. Values of organic carbon in the Nordic Seas' water masses, the amount of carbon input from river runoff ...
Jeansson, Emil   +19 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A1045_East_Carbon_High_School_0041_new_HD_18_fps

open access: yes, 1958
Film showing the East Carbon High School football team playing against an unidentified team at East Carbon. East Carbon wears the red helmets and blue jerseys.
East Carbon High School
core  

Losses of mineral soil carbon largely offset biomass accumulation fifteen years after whole-tree harvest in a northern hardwood forest [PDF]

open access: yes, 2019
Changes in soil carbon stocks following forest harvest can be an important component of ecosystem and landscape-scale C budgets in systems managed for bioenergy or carbon-trading markets.
Hamburg, Steven P   +7 more
core   +1 more source

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