Results 41 to 50 of about 177,651 (259)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Commission problems and countermeasures of integrated membrane technology in boiler make-up water system of a power plant

Gongye shui chuli
Based on the technical renovation project of boiler make-up water system in a power plant in North China，the design characteristics and operation mode of ultrafiltration-first stage reverse osmosis-second stage reverse osmosis-electrodeionization（EDI ...
ZHANG Kai, CHEN Yuqiang, CHEN Yang, LI Xiaojun, WANG Niuwang, LIU Guidong, HU Mingrui   +6 more
doaj   +1 more source

Experimental Study on Mineral Dissolution and Carbonation Efficiency Applied to pH-Swing Mineral Carbonation for Improved CO₂ Sequestration

Energies, 2023
Mineral carbonation incurs high operating costs, as large amounts of chemicals and energy must be used in the process. Its implementation on an industrial scale requires reducing expenditures on chemicals and energy consumption.
Natália R. Galina, Gretta L. A. F. Arce, Mercedes Maroto-Valer, Ivonete Ávila   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Would reducing chlorophyll content result in a higher photosynthesis nitrogen use efficiency in crops?

Food and Energy Security
Decreasing antenna size is considered a potential option for improving photosynthesis and increasing yield potential. Reducing chlorophyll content has been employed as a strategy to decrease antenna size.
Linxiong Mao, Qingfeng Song, Xiaoya Li, Huiqiong Zheng, Xin‐Guang Zhu   +4 more
doaj   +1 more source

A Review of DME Manufacturing: Process and Catalyst Studies [PDF]

E3S Web of Conferences
Consumption of fossil-based energy is increasing every year which has an impact on air, water and soil pollution. Therefore, alternative energy is needed to replace fossil fuels.
Anggraini Pamungkas Widya, Wahyu Budiman Anatta, Inayati, Margono, Siswahjono Tatag Sembodo Bregas, Mersitarini Dewi, Ardyatna Dimas, Mahendra Isya   +7 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source