Results 181 to 190 of about 236,141 (302)

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Scientific evidence does not support oyster farming as a marine carbon dioxide removal strategy for climate mitigation. [PDF]

Proc Natl Acad Sci U S A
Pernet F, Boyd PW, Dupont S, Gattuso JP, Gazeau F, Gobler CJ, Metian M, Tomasetti S, Williamson P.   +8 more
europepmc   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

ESTIMATING PHYTOSEQUESTRATION CAPACITY AND THE EFFECT OF ENVIRONMENTAL POLLUTION ON CARBON SEQUESTRATION OF SOME PLANT SPECIES AND ITS CHLOROPHYLL CORRELATION

FUUAST Journal of Biology
Carbon dioxide is present in the Earth's atmosphere and it acts as a major contributor in greenhouse gases. Exposure to carbon dioxide can have devastating effects on a person’s health.
AFFHAN SHOAIB, AIMAN SULTAN, SANA MINAI, SOHAIB AHMED, M. HASHIM ZUBERI   +4 more
doaj  

Iron deficiency and reduced exercise tolerance in adult Fontan patients. [PDF]

Front Pediatr
Bartczak-Rutkowska A, Trojnarska O, Nartowicz S, Markiewicz A, Lesiak M, Straburzyńska-Migaj E.   +5 more
europepmc   +1 more source

Insights Into CO2 Loss, pH Effects, and Tafel Kinetics in Ni Single Atom‐Driven Bicarbonate Electroreduction

Advanced Science, EarlyView.
Selective CO formation in bicarbonate electrolysis is achieved by retaining reactive CO2 and tuning pH, while the competing hydrogen evolution reaction occurs at the interface. The rate‐determining step couples the chemical equilibrium of bicarbonate/CO2 with electrochemical charge transfer, offering insight into optimizing reaction conditions for ...
Lin Li, Yi‐Jie Kong, Ting Zhang, Xu Han, Kristine Aalestrup, Steen Uttrup Pedersen, Xin‐Ming Hu, Kim Daasbjerg   +7 more
wiley   +1 more source

Optimizing Metabolic Assessment: Maximal Fat Metabolism, Lactate Dynamics, and Cardiorespiratory Determinants at Different Pedaling Frequencies. [PDF]

J Diabetes Res
Alkhatib A.
europepmc   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Decoupled timescales of organic carbon and phosphorus recycling in the global ocean. [PDF]

Proc Natl Acad Sci U S A
Sullivan MR, Primeau FW, Seo H, Camps-Castellà J, Inomura K, Martiny AC.   +5 more
europepmc   +1 more source

Electrochemical Hofmann Rearrangement for Modular Synthesis of Unsymmetrical Ureas and Late‐Stage Modification of Drugs

Advanced Science, EarlyView.
An electrochemical Hofmann rearrangement of amide involving amine or other amide nucleophiles has been developed. The use of NaI guarantees the feasibility and compatibility of the electrosynthesis protocol, which enables highly chemoselective synthesis of unsymmetrical N‐acylureas from two different amides, as well as the production of unsymmetrical ...
Xue‐Qing Mou, Xiao Zha, Yu‐Rui Jian, Shao‐Xing Zhong, Xin‐Yu Fu, Sheng‐Yang Xu, Wei Xiang, Bao‐Dong Cui, Yun Zhang, Yong‐Zheng Chen   +9 more
wiley   +1 more source