Results 1 to 10 of about 771,008 (307)

One-carbon metabolism in cancer [PDF]

British Journal of Cancer, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane, Alice C Newman, AS Tibbetts, B Chaneton, BC Blount, C Commisso, CA Lewis, CF Labuschagne, CF Woeller, D Hanahan, D Hanahan, D Kim, DD Anderson, E Currie, E Mullarky, F Daidone, F Kottakis, G Kikuchi, GM DeNicola, Gregory S. Ducker, GS Ducker, J Liu, J Meiser, J Ye, Jason W. Locasale, JJ Kamphorst, JW Locasale, K Snell, K Snell, K Snell, Katherine R. Mattaini, L Galluzzi, M Goulian, M Jain, M Kulis, Mahya Mehrmohamadi, ME Pacold, Ming Yang, MJ Osborn, ML Rose, ML Rose, OD Maddocks, OD Maddocks, Oliver D K Maddocks, Oliver D. K. Maddocks, PM Ueland, R Possemato, S Farber, S Kit, S Pollari, SJ Mentch, Swetha Bolusani, T Shlomi, WC Zhang, Y Fu, Z Ser   +55 more
core   +5 more sources

Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection

mBio, 2022
Cryptococcus neoformans is an important human fungal pathogen for which the external environment is its primary niche. Previous work has shown that two nonessential acetyl-CoA metabolism enzymes, ATP-citrate lyase (ACL1) and acetyl-CoA synthetase (ACS1),
Katy M. Alden, Andrew J. Jezewski, Sarah R. Beattie, David Fox, Damian J. Krysan   +4 more
doaj   +1 more source

Estimation of Carbon Metabolism in Saccharomyces cerevisiae Acclimatized to Glycerol Assimilation with Quantitative PCR

Microorganisms, 2022
Saccharomyces cerevisiae has the potential to produce value-added chemicals; however, this strain is restricted by using glycerol as a carbon source. Although acclimatization of S.
Akihito Nakanishi, Kuan Zhang, Riri Matsumoto, Naotaka Yamamoto   +3 more
doaj   +1 more source

The Pleiotropic Effects of Carbohydrate-Mediated Growth Rate Modifications in Bifidobacterium longum NCC 2705

Microorganisms, 2023
Bifidobacteria are saccharolytic bacteria that are able to metabolize a relatively large range of carbohydrates through their unique central carbon metabolism known as the “bifid-shunt”.
Stéphane Duboux, Solenn Pruvost, Christopher Joyce, Biljana Bogicevic, Jeroen André Muller, Annick Mercenier, Michiel Kleerebezem   +6 more
doaj   +1 more source

Genome-Wide Analysis of Invertase Gene Family, and Expression Profiling under Abiotic Stress Conditions in Potato

Biology, 2022
The potato is one of the most important and valuable crops in terms of consumption worldwide. However, abiotic stressors are the critical delimiters for the growth and productivity of potato.
Asad Abbas, Adnan Noor Shah, Anis Ali Shah, Muhammad Azhar Nadeem, Ahmad Alsaleh, Talha Javed, Saqer S. Alotaibi, Nader R. Abdelsalam   +7 more
doaj   +1 more source

Transcriptome Analysis of Two Near-Isogenic Lines with Different NUE under Normal Nitrogen Conditions in Wheat

Biology, 2021
Nitrogen (N) is an essential nutrient element for crop productivity. Unfortunately, the nitrogen use efficiency (NUE) of crop plants gradually decreases with the increase of the N application rate.
Xinbo Zhang, Fujian Li, Yonggang Ding, Quan Ma, Yuan Yi, Min Zhu, Jinfeng Ding, Chunyan Li, Wenshan Guo, Xinkai Zhu   +9 more
doaj   +1 more source

Mechanisms Behind the Indirect Impact of Metabolic Regulators on Virulence Factor Production in Staphylococcus aureus

Microbiology Spectrum, 2022
Staphylococcus aureus is a human skin pathogen capable of causing invasive infections in many tissues in the human body. The host of virulence factors, such as toxins and proteases, available to S.
Amelia C. Stephens, Lance R. Thurlow, Anthony R. Richardson   +2 more
doaj   +1 more source

Portable Measurement System for in situ Estimation of Oxygen and Carbon Fluxes of Submerged Plants

Frontiers in Plant Science, 2021
The metabolism of submerged plants is commonly characterized by oxygen development. The turnover rates of carbon dioxide and other inorganic carbon species, however, are assessed only at distinct points in time after incubation or calculated through ...
Annika Schrumpf, Andreas Lengerer, Nicola Schmid, Marian Kazda   +3 more
doaj   +1 more source

Quantitative Proteomic Profiling of Marine Diatom Skeletonema dohrnii in Response to Temperature and Silicate Induced Environmental Stress

Frontiers in Microbiology, 2021
Global warming is expected to reduce the nutrient concentration in the upper ocean and affect the physiology of marine diatoms, but the underlying molecular mechanisms controlling these physiological changes are currently unknown.
Satheeswaran Thangaraj, Satheesh Kumar Palanisamy, Guicheng Zhang, Guicheng Zhang, Jun Sun   +4 more
doaj   +1 more source

Exogenous Si Mitigates the Effects of Cinnamic-Acid-Induced Stress by Regulating Carbon Metabolism and Photosynthetic Pigments in Cucumber Seedlings

Agronomy, 2022
(1) Background: Cinnamic acid (CA) is a harmful substance secreted by the roots of continuous-cropping crops. (2) Methods: This study aimed to investigate how exogenous Si affects chlorophyll content and carbon metabolism in cucumber seedlings under CA ...
Jian Lyu, Li Jin, Xin Meng, Ning Jin, Shuya Wang, Linli Hu, Guobin Zhang, Yue Wu, Shilei Luo, Jihua Yu   +9 more
doaj   +1 more source