Results 161 to 170 of about 378,895 (264)

Causal effects of single-carbon metabolism and vitamin levels on autism spectrum disorder risk: a bidirectional Mendelian randomized study. [PDF]

Ital J Pediatr
Zhu J, Yi Y, Ma L, Tao S, Sun J, Zhang D, Sun X, Ding K.   +7 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Vibrational spectroscopy methodology for profiling of mixed carbon metabolism in carotenogenic and oleaginous Mucor circinelloides. [PDF]

Microb Cell Fact
Dzurendová S, Almklov Magnussen E, Shapaval V, Kohler A, Zimmermann B.   +4 more
europepmc   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Tyrosine phosphorylation coupling of one-carbon metabolism and virulence in an endogenous pathogen. [PDF]

Proc Natl Acad Sci U S A
Stocke KS, Pandey SD, Jin S, Perpich JD, Yakoumatos L, Kosaki H, Wilkey DW, Fitzsimonds ZR, Vashishta A, Snider I, Sriwastva MK, Li H, Jin JZ, Miller DP, Merchant ML, Bagaitkar J, Uriarte SM, Potempa J, Lamont RJ.   +18 more
europepmc   +1 more source

The control of photosynthetic carbon metabolism.

Science (New York, N.Y.), 1970
openaire   +4 more sources

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Global Control of Phosphotransferase System-Mediated Carbon Metabolism by CRP Is Associated with Metabolic Homeostasis and Virulence in <i>Klebsiella pneumoniae</i>. [PDF]

Microorganisms
Liu S, Guan Y, Zhang Y, Niu M, Yang K, Du Y.   +5 more
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

One-Carbon Metabolism and Midbrain Dopaminergic Cells in Lesch-Nyhan Disease. [PDF]

Mol Syndromol
Alsuwaidi S, Ernst C.
europepmc   +1 more source