Results 51 to 60 of about 629,831 (358)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Time-Varying Impacts of Carbon Price Drivers in the EU ETS: A TVP-VAR Analysis

Frontiers in Environmental Science, 2021
This study analyzes the impacts of different drivers on the pricing of EU carbon futures in various periods by using the time-varying parameter vector autoregressive (TVP-VAR) model.
Peng Li, Hao Zhang, Yongna Yuan, Aimin Hao   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Stimulation and Coordination Mechanisms of the Carbon Emission Trading Market of Public Buildings in China

Frontiers in Energy Research, 2021
The most important issue related to the establishment of carbon emission trading in China is how to motivate the owners of public buildings to participate.
Lingyan Li, Mimi Duan, Xiaotong Guo, Xiaotong Guo, Yao Wang   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Enhanced Carbon Price Forecasting Using Extended Sliding Window Decomposition with LSTM and SVR

Mathematics
Accurately forecasting carbon prices plays a vital role in shaping environmental policies, guiding investment strategies, and accelerating the development of low-carbon technologies.
Xiangjun Cai, Dagang Li, Li Feng
doaj   +1 more source

Carbon Risk and Equity Prices

SSRN Electronic Journal, 2023
AbstractWe study the effects of carbon transition risk on equity prices in the United States and Europe using disclosed carbon intensity data and find a negative effect on the cross section of returns and a negative carbon premium for the period 2009–2019.
Enders, Arthur, Lontzek, Thomas Siegmund, Schmedders, Karl, Thalhammer, Marco Simon   +3 more
openaire   +3 more sources

Emissions trading, carbon pricing, and the impact on carbon producing firms : a study of phase III of the European Union Emissions Trading Scheme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business (Finance) at Massey University, Palmerston North, New Zealand [PDF]

, 2018
This thesis examines the firm level impact of the European Union Emissions Trading Scheme (EU ETS), the ability to hedge carbon price, and the determinants of carbon price. The analysis focuses on phase III of the EU ETS.
Maddox, Grace Emily
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source