Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Observations of neutral carbon in 29 high-z lensed dusty star forming galaxies and the comparison of gas mass tracers [PDF]
Gayathri Gururajan +12 more
openalex +1 more source
Fluorine in a Carbon-Enhanced Metal-Poor Star
The fluorine abundance of the Carbon-Enhanced Metal-Poor (CEMP) star HE 1305+0132 has been derived by analysis of the molecular HF (1-0) R9 line at 2.3357 microns in a high-resolution (R = 50,000) spectrum obtained with the Phoenix spectrometer and ...
Beers, T. C. +5 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Detection of Lead in the Carbon-rich, Very Metal-poor Star LP 625-44: A Strong Constraint on [CLC][ITAL]s[/ITAL][/CLC]-Process Nucleosynthesis at Low Metallicity [PDF]
Wako Aoki +4 more
openalex +1 more source
Immunotoxicity of Carbon-Based Nanomaterials, Starring Phagocytes [PDF]
Tereza Švadláková +5 more
openalex +1 more source
CII, CI, and CO in the massive star forming region W3 Main
We have used the KOSMA 3m telescope to map the core 7'x5' of the Galactic massive star forming region W3Main in the two fine structure lines of atomic carbon and four mid-J transitions of CO and 13CO.
Bruell, M. +5 more
core +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Large-scale structure and kinematics of the Magellanic Clouds from carbon star studies [PDF]
M. Azzopardi, E. Rebeirot
openalex +1 more source
HE 1015-2050: Discovery of a Hydrogen-deficient carbon star at high galactic latitude
Medium resolution spectral analysis of candidate Faint High Latitude Carbon (FHLC) stars from Hamburg/ESO survey has given us the potential to discover objects of rare types.
Alcock +20 more
core +1 more source

