Results 71 to 80 of about 1,069,829 (300)

Transcritical Carbon Dioxide Charge-Discharge Energy Storage with Integration of Solar Energy [PDF]

, 2019
New and improved energy storage technologies are required to overcome non-dispatchability, which is the main challenge for the successful integration of large shares of renewable energy within energy supply systems.
Becerra Villanueva, José Antonio, Calderón, Beatriz, Carvalho, Monica, Chacartegui, Ricardo, Fernández, Reyes   +4 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Great SCO2T! Rapid tool for carbon sequestration science, engineering, and economics

, 2020
CO2 capture and storage (CCS) technology is likely to be widely deployed in coming decades in response to major climate and economics drivers: CCS is part of every clean energy pathway that limits global warming to 2C or less and receives significant CO2
Ampomah, Bachu, Bachu, Bielicki, Bielicki, Bielicki, Bourcier, Chen, Chen, Grant, Harp, Hoover, Jordan, Keating, Keating, Linstrom, Manual GUs, Metcalfe, Middleton, Middleton, Middleton, Middleton, Middleton, Middleton, Middleton, Middleton, Mingé, NETL, Nordbotten, Oldenburg, Pawar, Quintessa, Rogelj, Rogelj, Stauffer, Stauffer, Viswanathan, Warwick, Watson, Zhang, Zhang, Zhang, Zyvoloski, Zyvoloski, Zyvoloski   +44 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Sieving pore design enables stable and fast alloying chemistry of silicon negative electrodes in Li-ion batteries

Nature Communications
Ideal silicon negative electrodes for high-energy lithium-ion batteries are expected to feature high capacity, minimal expansion, long lifespan, and fast charging.
Jiaxing He, Youzhi Deng, Junwei Han, Tianze Xu, Jiangshan Qi, Jinghong Li, Yibo Zhang, Ziyun Zhao, Qi Li, Jing Xiao, Jun Zhang, Debin Kong, Wei Wei, Shichao Wu, Quan-Hong Yang   +14 more
doaj   +1 more source

Enhancing Computational Precision for Lattice Boltzmann Schemes in Porous Media Flows

Computation, 2016
We reassess a method for increasing the computational accuracy of lattice Boltzmann schemes by a simple transformation of the distribution function originally proposed by Skordos which was found to give a marginal increase in accuracy in the original ...
Farrel Gray, Edo Boek
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Fabricating 2D MoS2 with Edge Sulfur Vacancy Defects by Heavy Ion Bombardment Shear‐Exfoliation for Enhanced Sodium Storage

Advanced Science
Vacancy engineering is widely considered an effective approach to modulate the internal electronic structure of electrode materials, enhancing charge‐transfer processes/reactions and leading to excellent energy storage properties.
Feiyan Mu, Siqi Li, Dongqi Zhang, Qing Zhang, Zhe Hu, Ye Han, Zhixin Tai, Yajie Liu   +7 more
doaj   +1 more source