Results 131 to 140 of about 6,883 (166)

Meloxicam Carbopol-Based Gels: Characterization and Evaluation

Current Drug Delivery, 2011
To formulate and evaluate the hydrogels containing meloxicam for topical application and also compare the effect of penetration enhancers on release of drug.Meloxicam gels were prepared by dispersion method using carbopol-940 and 934 (1%w/w) as rate controlling polymer and drug penetration enhancers such as tween 80, oleic acid and sesame oil in the ...
Rashmi, Sareen, Sandeep, Kumar, G D, Gupta   +2 more
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Antiviral activity of carbopol, a cross-linked polycarboxylate

Archives of Virology, 1976
Carbopol, a polymer of acrylic acid cross-linked with allylsucrose, was found to impart resistance to virus infection in mice which received an intraperitoneal injection of the polycarboxylate 1 or 4 days before either intravenous vaccinia virus challenge or intranasal herpes simplex virus challenge.
E, de Clercq, M, Luczak
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Production of Carbopol® 974P and Carbopol® 971P Pellets by Extrusion‐Spheronization: Optimization of the Processing Parameters and Water Content

Drug Development and Industrial Pharmacy, 2004
Pellets obtained by extrusion-spheronization represent multiparticulate dosage forms whose interest in intestinal drug delivery can be potentiated and targeted through bioadhesive properties. However, adhesion itself makes the process difficult or even impossible.
N, Mezreb, Christine, Charrueau, P, Boy, P, Allain, J C, Chaumeil   +4 more
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Mucoadhesive suppositories of ramosetron hydrochloride utilizing Carbopol®

International Journal of Pharmaceutics, 2000
Suppositories are the preferable dosage form for patients at home or experiencing nausea. Serotonin (5-HT(3))-receptor antagonists are used to treat vomiting in intravenous or oral administration but not suppository form. Ramosetron hydrochloride (RAM) is a new 5-HT(3) antagonist which effectively inhibits vomiting, and we prepared RAM suppositories ...
R Yahagi, Y Machida, H Onishi, Y Machida
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Properties of Carbopol Solutions as Models for Yield-Stress Fluids

Journal of Food Science, 2002
ABSTRACT: The effect of pH on the non‐Newtonian viscosity (η)of aqueous Carbopol 940 solutions is presented with high resolution (pH increments about 0.4) between pH = 2.8 and 12.7. Aqueous NaOH was used to adjust pH of 1.48 wt % Carbopol solutions.
A Afacan, M C Williams, P A Tanguy
exaly   +2 more sources

Carbopol-gelatin coacervation and drug microencapsulation

Drug Development and Industrial Pharmacy, 1983
AbstractCarbopol-gelatin coacervates were recovered as water-insoluble powder which when suspended in water gave a highly disperse system.Glycerol as a protective against coacervate deformation, formaldhyde as a denaturant and some monohydric aliphatic alcohols as flocculating agents were variables studied.
Mohamed A Elegakey, Nazik A. Elgindy
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Rheological properties of Carbopol containing nanoparticles

Journal of Rheology, 2011
In this study we explored the rheological characteristics of Carbopol C934 gel (polyacrylic acid) containing SUS304 spherical nanoparticles of 100 nm as a simulant of gel propellants containing metal fuels. In comparison with the pure Carbopol gel, the SUS nanoparticle filled Carbopol gel exhibited stronger shear thinning and higher yield stress.
Gookhyun Baek, Chongyoup Kim
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In-vitro bioadhesion of carbopol hydrogels

International Journal of Pharmaceutics, 1996
The main goal of this work was to study the adhesive capacity of hydrogels obtained from carbopol, this was achieved using a tensile tester in which adhesion work was the main parameter. The intended use of these hydrogels was the buccal administration of propanolol HCl.
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Extrusion-Spheronization of Blends of Carbopol 934 and Microcrystalline Cellulose

Drug Development and Industrial Pharmacy, 2001
We evaluated the effects of several process variables on the pharmaceutical and drug release properties of extrusion-spheronization pellets of blends of Carbopol 934 and microcrystalline cellulose (MCC) containing a high proportion of Carbopol. The model drug was theophylline. Rheological monitoring during mixing was by mixer torque rheometry. Carbopol:
A, Gómez-Carracedo, C, Alvarez-Lorenzo, J L, Gómez-Amoza, R, Martínez-Pacheco, C, Souto, A, Concheiro   +5 more
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Preparation and characterization of enrofloxacin/carbopol complex in aqueous solution

Archives of Pharmacal Research, 2004
Since the bitter taste of enrofloxacin apparently limit the patient compliance in the oral formulations of the antibacterial agent, the masking of the taste is essential for the improvement of the therapeutic effectiveness. Therefore, this study was carried out to examine the feasibility of taste masking of enrofloxacin by the retardation of its ...
Myung-Kwan, Chun, Hoo-Kyun, Choi
openaire   +2 more sources