Results 31 to 40 of about 14,956 (151)

Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery

Acta Physiologica, Volume 241, Issue S734, July 2025.
ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley   +1 more source

Continuous Renal Replacement Therapy: Application of Kidney Disease Improving Global Outcomes Guidelines for Treatment Prescription in Dogs With Acute Kidney Injury and Outcome Prediction

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Continuous renal replacement therapy (CRRT) is routinely used in human patients with acute kidney injury (AKI) but studies in dogs are scarce. Objective To describe CRRT in dogs and assess the utility of a previously validated scoring system for dogs with AKI undergoing hemodialysis, and the Acute Patient Physiological and ...
Hilli Raskansky, Yaron Bruchim, Ran Nivy
wiley   +1 more source

Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique

JOR SPINE, Volume 8, Issue 2, June 2025.
The current study improves cyber toxicology as a method of evaluating environmental toxicity and molecular biological qualities in addition to clarifying the possible molecular pathways of nicotine‐induced senescence in IVDD. ABSTRACT Aim Through the use of network toxicology, the research sought to determine whether cellular senescence and associated ...
Chen Jiang, Chao Song, Chaoqi Chen, Baoxin Shen, Lei Yang, Chi Zhang, Fei Liu, Xiaofei Wu, Feng Chen   +8 more
wiley   +1 more source

Health Hazard Manual for Firefighters [PDF]

, 1990
[Excerpt] Firefighters, as well as victims, can be exposed to a variety of toxic substances during a fire. Some of these toxicants are particularly insidious because they are produced by thermal decomposition before smoke makes a fire ...
Brown, Nellie J.
core   +1 more source

Haemoglobin mass and running time trial performance after recombinant human erythropoietin administration in trained men [PDF]

, 2013
<p>Recombinant human erythropoietin (rHuEpo) increases haemoglobin mass (Hbmass) and maximal oxygen uptake (v˙ O2 max).</p> <p>Purpose: This study defined the time course of changes in Hbmass, v˙ O2 max as well as running time trial ...
A Lucia, AJ Brien, B Berglund, BD Levine, C Ahlgrim, C Lundby, C Lundby, C Lundby, CC Chang, CP Alfrey, D Boning, Diresibachew H. Wondimu, DL Costill, DP Wilkerson, Elias T. Zambidis, Evangelia Daskalaki, G Banfi, G Ninot, G Russell, GP Millet, H Ehrenreich, I Mujika, JD Belcher, JJ Thomsen, JM Kirkeberg, John D. McClure, Jérôme Durussel, K Heinicke, K Miskowiak, KI Birkeland, L Rice, L Rice, M Audran, M Brines, Martin Anderson, Neal Padmanabhan, NV Olsen, P Connes, P Rasmussen, PB Laursen, R Parisotto, Rajan K. Patel, RJ Shephard, RR Engel, RS Franco, SW Ryter, TD Noakes, TD Noakes, Tushar Chatterji, W Jelkmann, W Schmidt, Yannis P. Pitsiladis   +51 more
core   +2 more sources

Does traffic‐related air pollution exposure alter blood gas parameters in recreationally trained male cyclists during prolonged endurance exercise?

Physiological Reports, Volume 13, Issue 11, June 2025.
Changes in blood gas parameters following a 50‐km cycling time trial performed in a real‐world air‐polluted environment. Abstract Exposure to air pollution has been a significant challenge in large cities as São Paulo, Brazil, particularly for individuals exercising outdoors. The increasing on ventilation (VE) during physical effort can lead to greater
André C. Silveira, Júlio S. Hasegawa, Ramon Cruz, Monique Matsuda, Mônica V. Marquezini, Adriano Eduardo Lima‐Silva, Paulo Saldiva, Michael S. Koehle, Rômulo Bertuzzi   +8 more
wiley   +1 more source

Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid [PDF]

, 2012
Carbon monoxide (CO) poisoning leads to demyelination of cerebral white matter (CWM) fibers, causing chronic neuropsychiatric symptoms. To clarify whether fractional anisotropy (FA) from diffusion tensor imaging in the centrum semiovale can depict ...
Atsuhiko Koeda, Hideaki Nishimoto, Kiyoshi Mori, Kuniaki Ogasawara, Makoto Sasaki, Shinsuke Narumi, Shunrou Fujiwara, Takaaki Beppu   +7 more
core   +1 more source

Accidental Alkyl Nitrite (Poppers) Ingestion in a 37‐Year‐Old Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT This case demonstrates severe methemoglobinemia in a male patient following accidental ingestion of alkyl nitrites (“Poppers”). Prompt recognition and treatment with methylene blue ensured rapid recovery. Clinicians must consider this condition in patients with unexplained cyanosis and discordant oxygen saturation.
Laurie‐Anne De Pauw, Youcef Guechi, Jessica Schwaller   +2 more
wiley   +1 more source

A bibliography of published information relevant to fire toxicity [PDF]

A bibliography containing 883 references in the field of fire toxicity is presented to assist in literature searches to help reduce human fire ...
Cumming, H. J., Hilado, C. J., Kourtides, D. A., Parker, J. A.   +3 more
core   +1 more source

An agnostic study of donor and component factors associated with transfusion‐related changes in laboratory markers

Transfusion, Volume 65, Issue 5, Page 886-896, May 2025.
Abstract Background Donor and red blood cell (RBC) component factors may affect patient outcomes after RBC transfusions, but data on the magnitude and consequences of these associations are limited. Study Design and Methods In this retrospective cohort study, we analyzed associations between 10 donor and component factors—including donor age ...
Lucas D. Ekström, Mark Clements, Nareg Roubinian, Jingcheng Zhao, Torsten Dahlén, Michael P. Busch, Gustaf Edgren   +6 more
wiley   +1 more source