Protonation and ring closure of stereoisomeric alpha-substituted cinnamic acids in superacidic media studied by 13C NMR spectroscopy and computations [PDF]
Five alpha-substituted cinnamic acids [(E)- and (Z)-2,3-diphenyl-, (E)- and (Z)-3-(2-methoxyphenyl)-2-phenyl- and (E)-2-(2-methoxyphenyl)-3-phenyl-propenoic acids] have been protonated in fluorosulfonic acid at -78 degrees C, Protonation of the ...
Burrichter, Arwed +5 more
core +1 more source
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu +8 more
wiley +1 more source
Pyrazine Carboxylic Acid Derivatives of Dichlorobis(Cyclopentadienyl)titanium(IV)
Reactions of dichlorobis(cyclopentadienyl)titanium(IV) with pyrazine carboxylic acids viz. 2-pyrazine carboxylic acid (2-PzCH), 5-methyl-2-pyrazine carboxylic acid (MPzCH) and 2,3-pyrazine dicarboxylic acid (2,3-PzDCH2) were carried out in different ...
Satish Chandra Dixit, Rohit Kumar Singh
doaj +1 more source
Potentiostatic infrared titration of 11-Mercaptoundecanoic acid monolayers [PDF]
Acknowledgment This work was supported by the Spanish DGICYT under grant CTQ2008-00371 and by the Junta de Andalucía under grant P07-FQM-02492.Peer ...
Andreu, Rafael +3 more
core +2 more sources
Device Integration Technology for Practical Flexible Electronics Systems
Flexible device integration technologies are essential for realizing practical flexible electronic systems. In this review paper, wiring and bonding techniques critical for the industrial‐scale manufacturing of wearable devices are emphasized based on flexible electronics.
Masahito Takakuwa +5 more
wiley +1 more source
Modeling the hydrolysis of perfluorinated compounds containing carboxylic and phosphoric acid ester functions, alkyl iodides, and sulfonamide groups [PDF]
Temperature dependent rate constants were estimated for the acid- and base-catalyzed and neutral hydrolysis reactions of perfluorinated telomer acrylates (FTAcrs) and phosphate esters (FTPEs), and the SN1 and SN2 hydrolysis reactions of fluorotelomer ...
Kaya Forest, Sierra Rayne
core +1 more source
Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes [PDF]
Hen egg-white lysozyme has long been the paradigm for enzymatic glycosyl hydrolysis with retention of configuration, with a protonated carboxylic acid and a deprotonated carboxylate participating in general acid-base catalysis.
Blake C. C. F. +28 more
core +3 more sources
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
5-Methylisoxazole-4-carboxylic acid
In the title compound, C5H5NO3, the molecule lies on a crystallographic mirror plane with one half-molecule in the asymmetric unit. An intramolecular C—H...O interaction is present.
Wen-Yuan Wu, Wei Xu, De-Cai Wang
doaj +1 more source
Cobalt-catalyzed highly enantioselective hydrogenation of α,β-unsaturated carboxylic acids
A large number of marketed drugs contains a chiral carboxylic acid scaffold. Here, the authors report the asymmetric hydrogenation of α,β-unsaturated carboxylic acids to α-chiral carboxylic acids using a cobalt catalyst bearing an electron-donating ...
Xiaoyong Du +8 more
doaj +1 more source

