Results 21 to 30 of about 409,864 (304)

New Furan Derivatives from a Mangrove-Derived Endophytic Fungus Coriolopsis sp. J5

open access: yesMolecules, 2017
Six new furan derivatives, named 5-(3-methoxy-3-oxopropyl)-furan-2-carboxylic acid (1), 1-(5-(2-hydroxypropanoyl)-furan-2-yl)-pentan-3-one (2), 2-hydroxy-1-(5-(1-hydroxypentyl)-furan-2-yl)-propan-1-one (3), 1-(5-(1,2-dihydroxypropyl)-furan-2-yl)-pentan-1-
Liang-Liang Chen   +6 more
doaj   +1 more source

A facile and chemoselectivity in synthesis of 4-chloro-N-(4-((1-hydroxy-2-methylpropan-2-yl)oxy)phenethyl)benzamide, the alcohol derivative of Bezafibrate

open access: yesResults in Chemistry, 2022
A facile method for the reduction of carboxylic acid group of Bezafibrate, an approved drug, is described. The selective reduction of carboxylic acid group to corresponding alcohol was carried out by activation of the carboxylic acid moiety via mixed ...
Greesha N. Majethia   +2 more
doaj   +1 more source

Indole-3-Carboxylic Acid Enhanced Anti-cancer Potency of Doxorubicin via Induction of Cellular Senescence in Colorectal Cells [PDF]

open access: yesActa Poloniae Pharmaceutica
Background: Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Doxorubicin (DOX) is a widely utilized chemotherapy drug, but its efficacy is limited due to dose-dependent toxicity.
Yao Zhou   +4 more
doaj   +1 more source

Synthesis of biodegradable polyesteramides with pendant functional groups [PDF]

open access: yes, 1992
Morpholine-2,5-dione derivatives having substituents with benzyl-protected carboxylic acid, benzyloxycarbonyl-protected amine and p-methoxy-protected thiol groups, respectively, were prepared in 29-58% yield by cyclization of the corresponding N-[(2RS ...
Dijkstra, Pieter J.   +2 more
core   +3 more sources

Pyrimidine-4-carboxylic acid

open access: yesActa Crystallographica Section E, 2013
The crystal structure of the title compound, C5H4N2O2, is built of acid molecules located on a mirror plane. They form sheets stacked along the b-axis direction.
Katarzyna Kiegiel   +2 more
doaj   +1 more source

The thermodynamic landscape of carbon redox biochemistry [PDF]

open access: yes, 2018
Redox biochemistry plays a key role in the transduction of chemical energy in all living systems. Observed redox reactions in metabolic networks represent only a minuscule fraction of the space of all possible redox reactions.
Aspuru-Guzik, Alán   +7 more
core   +1 more source

Adamantane carboxylic acids demonstrate mitochondrial toxicity consistent with oil sands-derived naphthenic acids

open access: yesEnvironmental Advances, 2021
Naphthenic acids (NAs) are thought to be a primary cause of toxicity of oil sands process-affected water (OSPW). The purpose of this study was to determine if commercially available adamantane carboxylic acids act by mitrochondrial mechanisms similar to ...
Kate I. Rundle   +4 more
doaj   +1 more source

Spectroscopic data of 6-(N-methyl-pyridin-2-ylcarbamoyl)-pyridine-2-carboxylic acid methyl ester isomers

open access: yesData in Brief, 2019
This paper provided spectroscopic data that is relevant with research article entitled “Synthesis and structural characterization of 6-(N-methyl-pyridin-2-ylcarbamoyl)-pyridine-2-carboxylic acid methyl ester Isomer” (Kadir et al., 2017) [1].
M.A. Kadir   +3 more
doaj   +1 more source

Bromopyrrole alkaloids from the caribbean sponge Agelas cerebrum

open access: yesQuímica Nova, 2011
Bioguided fractionation of Agelas cerebrum crude extract resulted in isolation of four bromopyrrole and four bromopyrrole aminoimidazole alkaloids, identified as 5-bromopyrrole-2-carboxylic acid (1), 4-bromopyrrole-2-carboxylic acid (2), 3,4-bromopyrrole-
Erik L. Regalado   +4 more
doaj   +1 more source

Chemical defenses of the Caribbean sponges Agelas wiedenmayeri and Agelas conifera [PDF]

open access: yes, 2000
Previous studies have determined that Caribbean reef sponges of the genus Agelas are chemically defended from fish predation by brominated pyrrole alkaloids, and that the compounds responsible for this defense have been elucidated for one species, Agelas
Assmann, M.   +3 more
core   +1 more source

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