Results 161 to 170 of about 333,250 (353)

Inhibition of anaphylactic histamine release from rat peritoneal mast cells by disodium cromoglycate, 6, 7-dihydro-6, 8, 8, 10-tetramethyl-8H-pyrano-[3, 2-G] chromon-2-carboxylic acid (EAA) and tranilast

, 1987
Shigeki Ikeda
openalex   +2 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Synthesis of new 3'-N-alcyl and 3'-N-alkyl 3'-amino-3'-deoxythymidine derivatives

Тонкие химические технологии, 2006
A number of new 3'-N-alcyl and 3'-N-alkyl derivatives of 3'-amino-3'-deoxythymidine was obtained by means of nucleoside and carboxylic acids condensation.
K. V. Seregin, N. A. Iltyakova, M. V. Chudov, V. I. Shvets   +3 more
doaj  

Conjugation of Tryptamine to Biologically Active Carboxylic Acids in Order to Create Prodrugs [PDF]

, 2021
Colin G. Miller
openalex   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Influence of carboxylic acids on wheat carboxypeptidase - Their inhibition modes and effect of citric acid on stabilization in spray drying.

, 1989
Hironori Umetsu, Eiji Ichishima
openalex   +2 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Acridinium amidate as a hydrogen-bonding photocatalyst for direct decarboxylative alkylation of native carboxylic acids. [PDF]

Chem Sci
Truong DA, Mori S, Ninomiya T, Niwa R, Maeda B, Fujino H, Inoue M, Ohmatsu K, Ooi T.   +8 more
europepmc   +1 more source

Recent developments in decarboxylative cross-coupling reactions between carboxylic acids and N–H compounds

, 2019
Sattar Arshadi, Saeideh Ebrahimiasl, Akram Hosseinian, Aazam Monfared, Esmail Vessally   +4 more
openalex   +2 more sources