Results 221 to 230 of about 547,981 (341)

Identification of neural crest and melanoma cancer cell invasion and migration genes using high‐throughput screening and deep attention networks

Developmental Dynamics, EarlyView.
Abstract Background Cell migration and invasion are well‐coordinated in development and disease but remain poorly understood. We previously showed that the neural crest (NC) cell migratory wavefront shares a 45‐gene panel with other cell invasion phenomena.
J. C. Kasemeier‐Kulesa, S. Martina Perez, R. E. Baker, P. M. Kulesa   +3 more
wiley   +1 more source

Microbial metabolite trimethylamine-N-oxide facilitates colorectal inflammation-cancer transformation by blocking lysosomal degradation of Wnt signaling. [PDF]

Gut Microbes
Yang K, Liu Z, Wang H, Xiao Z, Zhao W, Gong W.   +5 more
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Multi-Omics Analysis Reveals the Mechanism of Exosome-Related Genes in Adrenocortical Carcinogenesis [PDF]

Zhiping Chen, Tengfei Liu, Weimin Chen, Guoyang Zhao   +3 more
openalex   +1 more source

CANCER BIOLOGY: Effects of dietary β-carotene and selenium on initiation and promotion of pancreatic carcinogenesis in azaserine-treated rats [PDF]

, 1996
M.J. Appel, R.A. Woutersen
openalex   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Antioxidant potential of naringin – a dietary flavonoid – in N-Nitrosodiethylamine induced rat liver carcinogenesis

, 2012
Prabu Thangavel, Ragunath Muthu, Manju Vaiyapuri   +2 more
openalex   +1 more source

Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics

Environmental and Molecular Mutagenesis, EarlyView.
Abstract As a part of the International Workshop on Genotoxicity Testing (IWGT) in 2022, a workgroup was formed to evaluate the level of validation and regulatory acceptance of transcriptomic biomarkers that identify genotoxic substances. Several such biomarkers have been developed using various molecular techniques and computational approaches. Within
Matthew J. Meier, Florian Caiment, J. Christopher Corton, Roland Frötschl, Yurika Fujita, Danyel Jennen, Roman Mezencev, Carole Yauk   +7 more
wiley   +1 more source

Corrigendum to Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. [PDF]

J Clin Invest
Van TM, Polykratis A, Straub BK, Kondylis V, Papadopoulou N, Pasparakis M.   +5 more
europepmc   +1 more source

Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis [PDF]

Yiwen Wang, Yue Wang, Wenjie Han, Mengzhen Han, Xiaolin Liu, Jianying Dai, Yuesheng Dong, Tao Sun, Junnan Xu   +8 more
openalex   +1 more source