Results 221 to 230 of about 534,637 (340)

Inhalation Carcinogenesis

open access: yesEcotoxicology and Environmental Safety, 1977
openaire   +2 more sources

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni   +8 more
wiley   +1 more source

The Efficacy and Safety of Intrapancreatic Bile Duct Resection Applied in Type I of Congenital Bile Duct Dilation: A Multicenter Control Cohort Study. [PDF]

open access: yesAnn Surg
Yang CZ   +26 more
europepmc   +1 more source

Exploring the Antiproliferative Activity of Flavolignans From the Leaves of Casearia arborea (Salicaceae)

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The Casearia genus (Salicaceae) is well known as a source of natural antitumor prototypes, as described for clerodane diterpenes. In this way, the dichloromethane phase from leaves of Casearia arborea was phytochemically evaluated in liquid chromatography coupled to high‐resolution mass spectrometry, furnishing flavonoid, flavolignan, and ...
Augusto L. Santos   +7 more
wiley   +1 more source

Dominant‐Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity

open access: yesChemBioChem, EarlyView.
Hetero‐tetramer dysfunction: Li–Fraumeni syndrome (LFS) is a hereditary cancer predisposition caused by mutations in the TP53 gene encoding the tumor suppressor p53. It is shown that p53 variants R337C and R337H, found in LFS, impair wild‐type (WT) p53 function by forming heterotetramers with reduced transcriptional activity.
Rui Kamada   +6 more
wiley   +1 more source

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