Proteomic profiling and scRNA sequencing identify signatures associated with <i>Helicobacter pylori</i> infection and risk of developing gastric cancer. [PDF]
Jin Y+9 more
europepmc +1 more source
Studies on sequential metabolic alterations in spontaneous mammary carcinogenesis. [PDF]
N A Sheth+3 more
openalex +1 more source
Gankyrin‐Protein Interactions in GI Cancers: A Novel Target of New Therapeutics
ABSTRACT Gankyrin (PSMD10) is a 25 kDa oncogenic protein and regulatory subunit of the 26S proteasome, characterized by a sevenfold ankyrin repeat domain. Gankyrin is overexpressed in various malignancies, particularly gastrointestinal (GI) cancers. Gankyrin contributes to tumorigenesis by modulating key signaling pathways and engaging in oncogenic ...
Shuang Li+4 more
wiley +1 more source
Correction: Integrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival. [PDF]
Tang W+7 more
europepmc +1 more source
Experimental carcinogenesis in the parotid glands of mice
Shoji ENOMOTO
openalex +2 more sources
Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley +1 more source
Integrative network toxicology and molecular docking reveal 4-Nonylphenol's multifaceted mechanisms in breast cancer pathogenesis. [PDF]
Jia C, Yang F.
europepmc +1 more source
Abstract Background Cell migration and invasion are well‐coordinated in development and disease but remain poorly understood. We previously showed that the neural crest (NC) cell migratory wavefront shares a 45‐gene panel with other cell invasion phenomena.
J. C. Kasemeier‐Kulesa+3 more
wiley +1 more source
Distinct microbial signatures of liquid biopsy samples during gastric carcinogenesis and insights from extracellular vesicle analysis. [PDF]
You HS, Park JY, Seo H, Kim BJ, Kim JG.
europepmc +1 more source