Results 291 to 300 of about 34,758 (354)

Assessment of performance of the profilers provided in the OECD QSAR toolbox for category formation of chemicals. [PDF]

Sci Rep
Aljallal MA, Chaudhry Q, Price NR.
europepmc   +1 more source

Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values. [PDF]

Front Toxicol
Builee T, Kennedy TA, Levelut V, Hahn MA, Bond S, Peterson MK, Hsia FK, Stornetta A, Erickson KJ, Ehman KD, Prabhakar B, Bagley BD, Parker SP.   +12 more
europepmc   +1 more source

Integrative analysis reveals SRD5A2 as a central mediator in PPCPs induced modulation of the prostate cancer immune microenvironment. [PDF]

Discov Oncol
Zhou T, Li Y, Ji P, Meng C, Liu Z, Zeng Z, Yang Y, Li T.   +7 more
europepmc   +1 more source

Injection of gentian violet 1% solution successfully identified the origin of aseptic mediastinitis: A case report. [PDF]

JTCVS Tech
Takehara M, Shimamoto T, Sakamoto K, Tamaoka K.   +3 more
europepmc   +1 more source

Carcinogenicity assessment: "modern toxicology" considerations from experience in the evaluation of a carbon nanotube. [PDF]

J Occup Health
Kanno J.
europepmc   +1 more source

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Carcinogenicity testing of drugs

1985
The dramatic advances in medicine in the last fifty years have stemmed in large part from extensive research to discover new effective medications for controlling and treating many types of diseases that afflict mankind. In the development of new drugs, an increasingly important aspect is to predict and assess any adverse effects that the products ...
G M, Williams, J H, Weisburger
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Carcinogenicity Testing of Drugs

JAMA: The Journal of the American Medical Association, 1980
To the Editor.— I agree with John C. Ballin, MD (242:26, 1979), that the results of studies in which large doses are given to animals for a lifetime do not necessarily mean that "such drugs or chemicals are carcinogenic in man when taken according to label directions." But the studies do not necessarily mean that such drugs or chemicals are not ...
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The peritoneal cell carcinogenicity test

Mutation Research Letters, 1986
The peritoneal cell carcinogenicity test, which is a new short-term in vivo-in vitro transformation test invented by Nashed (1981), was evaluated in the present report. The experimental design and materials used were as close as possible to those used by Nashed (1981).
Nielsen, Jesper B., Andersen, Ole
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Carcinogenicity Testing of Drugs

JAMA: The Journal of the American Medical Association, 1979
To the Editor.— The National Cancer Institute (NCI) has begun a long-term project of testing commonly used drugs for their possible carcinogenic effect in animals. In conducting these tests, the NCI uses a standard protocol that involves giving drugs for long periods (generally lifetime feeding) in large doses to mice, rats, and other experimental ...
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