Results 1 to 10 of about 711,467 (262)

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

MedComm, Volume 6, Issue 9, September 2025.
This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily
Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu   +7 more
wiley   +1 more source

Carcinoid Syndrome-Induced Ventricular Tachycardia

Case Reports in Cardiology, 2016
Introduction. Carcinoid tumors are rare neuroendocrine malignancies that secrete multiple bioactive substances. These bioactive substances are responsible for the carcinoid syndrome characterized by diarrhea, flushing, syncope, and right-sided valvular ...
Austin B. Rupp, Abdulmohsin Ahmadjee, Jack H. Morshedzadeh, Ravi Ranjan   +3 more
doaj   +1 more source

Drugs Affecting 5-HT Systems [PDF]

, 2013
Seminar transcriptIt was in the very early hours of a February morning in 1977 that I first looked down the microscope and saw yellow fluorescence, characteristic of 5-hydroxytryptamine (5-HT) in frozen sections of Octopus brain. After struggling for two
Overy, C, Tansey, EM
core  

Two‐Scope Technique for Tracheal Epithelial‐Myoepithelial Carcinoma‐A Rare Case Report and Review

Respirology Case Reports, Volume 13, Issue 9, September 2025.
Our case describes a rare tumour, tracheal epithelial‐myoepithelial carcinoma, that was successfully removed using a two‐scope technique (novel technique for tumour resection). The diagnosis was confirmed by comprehensive histopathological and immunohistochemical examination.
Saurabh Karmakar, Vinay Venugopal, Abdul Raouf Wani, Gaurav Kumar Singh, Debapriya Maji, Alpana Srivastava   +5 more
wiley   +1 more source

Contrast‐Enhanced Computed Tomography Imaging Features of Primary Hepatic Neuroendocrine Carcinoma in a 4‐Year‐Old French Bulldog

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
A 4‐year‐old female‐spayed French bulldog presented with symptoms of anorexia, lethargy, 22 and vomiting. Abdominal ultrasonography revealed multiple coalescing hyperechoic nodules 23 in the liver. Single‐phase contrast‐enhanced computed tomography (CT) scan showed 24 heterogeneous liver lobes with hyperattenuating parenchyma and multiple ...
Hyeonji Sim, Sung‐Soo Kim, Seoungyob Ahn, Amanda Jane Dennis, Kichang Lee, Hakyoung Yoon   +5 more
wiley   +1 more source

Cardiac Surgery and Transcatheter Intervention for Valvular Heart Disease in Carcinoid Syndrome: Risk Factors, Outcomes, and Evolving Therapeutic Strategies

Journal of Cardiovascular Development and Disease
Carcinoid heart disease (CHD) affects right-sided valves and causes significant mortality and morbidity. Even though the pathophysiology of the disease is not entirely understood, it is known that chronic exposure to high levels of circulating serotonin ...
Mariagrazia Piscione, Valeria Cammalleri, Giorgio Antonelli, Valeria Maria De Luca, Myriam Carpenito, Dario Gaudio, Nino Cocco, Antonio Nenna, Carmelo Dominici, Antonio Bianchi, Francesco Grigioni, Gian Paolo Ussia   +11 more
doaj   +1 more source

An unusual cause of hypoxia: getting to the heart of the matter

Echo Research and Practice, 2017
A 63-year-old female presented to hospital with progressive exertional dyspnoea over a 6-month period. In the year preceding her admission, she reported an intercurrent history of abdominal pain, diarrhoea and weight loss.
Daniel Hammersley, Aamir Shamsi, Mohammad Murtaza Zaman, Philip Berry, Lydia Sturridge   +4 more
doaj   +1 more source

Screening for malnutrition in patients with gastro-entero-pancreatic neuroendocrine tumours : a cross-sectional study [PDF]

, 2016
Objectives To investigate whether screening for malnutrition using the validated malnutrition universal screening tool (MUST) identifies specific characteristics of patients at risk, in patients with gastro-entero-pancreatic neuroendocrine tumours (GEP ...
Burch, Nicola, Darby, Catherine, Davies, Louise, Dimitriadis, Georgios K., Druce, Maralyn, Fletcher, Simon, Gopalakrishnan, Kishore, Hattersley, John G, Khan, Saboor, Qureshi, Sheharyar A., Randeva, Harpal S., Shatwell, William, Sothi, Sharmila, Weickert, Martin O., Wong, John L H   +14 more
core   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann, Milena Carolina Paz, Paola Sônego, Ana Carolina Contri Natal, Lívia Surita, Marcele Bettim Bandinelli, Luciana Sonne   +6 more
wiley   +1 more source

Thyroid lesions of neuroendocrine origin? Thinking of a “polka‐dotted” zebra! Case series from three Italian referral centers and review of the literature

Journal of Neuroendocrinology, Volume 37, Issue 9, September 2025.
Thyroid metastases from neuroendocrine neoplasm (NEN) should be considered in case of suspicious thyroid nodules in patients with a positive medical history of NEN, mainly of thoracic origin, even after many years from the initial diagnosis. The differential diagnosis from primary intrathyroidal NEN is challenging.
Tiziana Feola, Alessia Cozzolino, Federica Grillo, Maria Francesca Birtolo, Irene Aini, Erika Messina, Roberto Minotta, Alessia Filice, Isabella Zanata, Paola Razzore, Manila Rubino, Andrea M. Isidori, Annamaria Colao, Antongiulio Faggiano, Elisa Giannetta, on behalf of NIKE group, Irene Aini, Manuela Albertelli, Ylenia Alessi, Simone Antonini, Luigi Barrea, Elio Benevento, Maria Francesca Birtolo, Federica Campolo, Celeste Cantone, Silvia Carra, Rob‐erta Centello, Alessia Cozzolino, Federica De Cicco, Valentina Di Vito, Beatrice Fazzalari, Stefano Gay, Elisa Giannetta, Federica Grillo, Elia Guadagno, Valentina Guarnotta, Iderina Hasballa, Alice Laffi, Andrea Lania, Alessia Liccardi, Rossella Mazzilli, Erika Messina, Roberto Minotta, Giovanna Muscogiuri, Carla Pandozzi, Gabriella Pugliese, Giulia Puliani, Alberto Ragni, Manila Rubino, Rosaria Maddalena Ruggeri, Franz Sesti, Maria Grazia Tarsitano, Ludovica Verde, Giovanni Vitale, Virginia Zamponi, Isabella Zanata, Roberta Modica, Giuseppe Fanciulli, Anna La Salvia, Erika Maria Grossrubatscher, Francesco Ferrau, Alessandro Veresani, Flaminia Russo   +62 more
wiley   +1 more source